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Article

Polybrene induces neural degeneration by bidirectional Ca²⁺ influx-dependent mitochondrial and ER–mitochondrial dynamics

Hexadimethrine bromide (Polybrene) was once used clinically as a heparin neutralizer and has recently found use as a promoter in virus-mediated gene therapy trials and gene transfer in research. However, the p...

Feixiang Bao, Hongyan Shi, Mi Gao, Liang Yang, Lingyan Zhou… in Cell Death & Disease (2018)