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    Abnormal amino acid metabolism in patients with early stage Alzheimer dementia

    Plasma levels of several amino acids were studied in 14 patients with early stage probable Alzheimer's disease (AD) and 17 age-matched controls. In the AD patients a possible relationship between amino acid l...

    D. Fekkes, T. J. M. van der Cammen, C. P. M. van Loon in Journal of Neural Transmission (1998)

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    Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692Ala→Gly mutation

    Mutations at codons 717 and 670/671 in the amyloid precursor protein (APP) are rare genetic causes of familial Alzheimer’s disease (AD). A mutation at codon 693 of APP has also been described as the genetic d...

    P. Cras, F. van Harskamp, L. Hendriks, C. Ceuterick in Acta Neuropathologica (1998)

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    Improvement of spontaneous speech in early stage Alzheimer’s disease with rivastigmine

    Placebo-controlled trials have shown that rivastigmine can delay cognitive deterioration in patients with mild to moderate Alzheimer’s disease (AD). Benefits on cognitive functioning, as measured with the ADAS...

    E. G. Visch-Brink, W. Van Rhee-Temme in JNHA - The Journal of Nutrition, Health an… (2009)