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Article
Kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury
Objective. To investigate the kinetic and reversibility of mechanical ventilation-associated pulmonary and systemic inflammatory response in patients with acute lung injury (ALI).
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Article
Protective functions of intracellular heat-shock protein (HSP) 70-expression in patients with severe sepsis
Intracellular expression of heat-shock-protein 70 (HSP70) arose early in evolutionary development as a tool to protect cellular homeostasis. HSP70 detects proteins that are incorrectly folded or denatured. Th...
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Article
The PstI polymorphism of the endotoxin-inducible heat-shock protein 70–2 gene does not affect messenger RNA level in human whole-blood cultures
Objective: To determine whether the human leukocyte antigen linked biallelic heat-shock protein 70–2 (HSP70–2) gene polymorphism is associated with variable HSP70–2 messenger RNA express...
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Article
Endotoxin inhibits heat shock protein 70 (HSP70) expression in peripheral blood mononuclear cells of patients with severe sepsis
Objective: To investigate the ex vivo endotoxin-inducible heat shock protein 70 (HSP70) expression in the peripheral blood mononuclear cells (PBMC) of patients with severe sepsis in orde...