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Article
RBP-Jκ-dependent Notch signaling enhances retinal pigment epithelial cell proliferation in transgenic mice
The Notch signaling pathway is an ubiquitous cell–cell interaction mechanism, which is essential in controlling processes like cell proliferation, cell fate decision, differentiation or stem cell maintenance. ...
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Article
Notch and cancer: a double-edged sword
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Article
Notch and cancer: a double-edged sword
The highly conserved Notch signaling pathway plays pleiotropic roles during embryonic development and is important for the regulation of selfrenewing tissues. The physiological functions of this signaling casc...
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Article
Postoperative Störungen der kognitiven Leistungsfähigkeit bei älteren Patienten Die Ergebnisse der „International Study of Postoperative Cognitive Dysfunction” (ISPOCD 1)
Fragestellung: Störungen der kognitiven Leistungsfähigkeit nach operativen Eingriffen sind ein Problem, von dem besonders ältere Patienten betroffen zu sein scheinen. Das Ziel der vorliegenden in...
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Article
Regulation of metallothionein gene expression in Cd- or Zn-adapted RK-13 cells
We explored the molecular genetics underlying the massive induction of isoMTs by Zn2+ or Cd2+ in metal tolerant rabbit kidney (RK-13) sub-line cells, using band shift assays and Southern blotting analysis. In sub...
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Article
Steuerbare Ventrikel- oder Sub-arachnoidealfüllung bei der lumbalen und occipitalen Encephalographie