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  1. No Access

    Article

    Investigating the tissue specificity and prognostic impact of cis-regulatory cancer risk variants

    The tissue-specific incidence of cancers and their genetic basis are poorly understood. Although prior studies have shown global correlation across tissues for cancer risk single-nucleotide polymorphisms (SNPs...

    Ajay Subramanian, Shengqin Su, Everett J. Moding, Michael Sargent Binkley in Human Genetics (2023)

  2. No Access

    Article

    A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

    The next generation of genetically engineered mouse models of pancreatic cancer involving a new inducible dual-recombinase system that combines Flp-FRT and Cre-loxP.

    Nina Schönhuber, Barbara Seidler, Kathleen Schuck, Christian Veltkamp… in Nature Medicine (2014)

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    Article

    Strategies for optimizing the response of cancer and normal tissues to radiation

  4. More than half of all patients with cancer receive radiation therapy.

  5. Normal tissue tolerance for radiation...

    6. Everett J. Moding, Michael B. Kastan, David G. Kirsch in Nature Reviews Drug Discovery (2013)