410 Result(s)

Article

Germ granule compartments coordinate specialized small RNA production

Germ granules are biomolecular condensates present in most animal germ cells. One function of germ granules is to help maintain germ cell totipotency by organizing mRNA regulatory machinery, including small RN...

**angyang Chen, Ke Wang, Farees Ud Din Mufti, Demin Xu… in Nature Communications (2024)

Article

ATP6V0A1-dependent cholesterol absorption in colorectal cancer cells triggers immunosuppressive signaling to inactivate memory CD8⁺ T cells

Obesity shapes anti-tumor immunity through lipid metabolism; however, the mechanisms underlying how colorectal cancer (CRC) cells utilize lipids to suppress anti-tumor immunity remain unclear. Here, we show th...

Tu-**ong Huang, Hui-Si Huang, Shao-Wei Dong, Jia-Yan Chen… in Nature Communications (2024)

Article

Author Correction: ALKBH5-mediated m6A modification of IL-11 drives macrophage-to-myofibroblast transition and pathological cardiac fibrosis in mice

Tao Zhuang, Mei-Hua Chen, Ruo-** Wu, **g Wang, **-De Hu… in Nature Communications (2024)

Article

Whole-exome sequencing identifies protein-coding variants associated with brain iron in 29,828 individuals

Iron plays a fundamental role in multiple brain disorders. However, the genetic underpinnings of brain iron and its implications for these disorders are still lacking. Here, we conduct an exome-wide associatio...

Weikang Gong, Yan Fu, Bang-Sheng Wu, **gnan Du, Liu Yang… in Nature Communications (2024)

Article

Tamm-cavity terahertz detector

Efficiently fabricating a cavity that can achieve strong interactions between terahertz waves and matter would allow researchers to exploit the intrinsic properties due to the long wavelength in the terahertz ...

Xuecou Tu, Yichen Zhang, Shuyu Zhou, Wen**g Tang, Xu Yan… in Nature Communications (2024)

Article

Cholesterol efflux from C1QB-expressing macrophages is associated with resistance to chimeric antigen receptor T cell therapy in primary refractory diffuse large B cell lymphoma

Chimeric antigen receptor T (CAR-T) cell therapy has demonstrated promising efficacy in early trials for relapsed/refractory diffuse large B cell lymphoma (DLBCL). However, its efficacy in treating primary ref...

Zi-Xun Yan, Yan Dong, Niu Qiao, Yi-Lun Zhang, Wen Wu, Yue Zhu… in Nature Communications (2024)

Article

Curved carbon-plated shoe may further reduce forefoot loads compared to flat plate during running

Using a curved carbon-fiber plate (CFP) in running shoes may offer notable performance benefit over flat plates, yet there is a lack of research exploring the influence of CFP geometry on internal foot loading...

Yang Song, Xuanzhen Cen, Dong Sun, Kovács Bálint, Yan Wang… in Scientific Reports (2024)

Article

Saccharomyces boulardii combined with triple therapy alter the microbiota in the eradication of Helicobacter pylori infection

To assess the effectiveness and safety of combining Saccharomyces boulardii powder with triple therapy as a primary approach for eradicating H. pylori infection, a total of 144 patients who tested positive for H....

Yan Zhang, Bingyun Lu, Yu Dong, Yifeng Zhang, Qianming Du, Ye Chen… in Scientific Reports (2024)

Article

Real-time predictive model of extrauterine growth retardation in preterm infants with gestational age less than 32 weeks

The aim of this study was to develop a real-time risk prediction model for extrauterine growth retardation (EUGR). A total of 2514 very preterm infants were allocated into a training set and an external valida...

Liang Gao, Wei Shen, Fan Wu, Jian Mao, Ling Liu, Yan-Mei Chang… in Scientific Reports (2024)

Article

FBXO7 ubiquitinates PRMT1 to suppress serine synthesis and tumor growth in hepatocellular carcinoma

Cancer cells are often addicted to serine synthesis to support growth. How serine synthesis is regulated in cancer is not well understood. We recently demonstrated protein arginine methyltransferase 1 (PRMT1) ...

Li Luo, **ngyun Wu, Jiawu Fan, Lixia Dong, Mao Wang, Yan Zeng… in Nature Communications (2024)

Article

Complete telomere-to-telomere genomes uncover virulence evolution conferred by chromosome fusion in oomycete plant pathogens

Variations in chromosome number are occasionally observed among oomycetes, a group that includes many plant pathogens, but the emergence of such variations and their effects on genome and virulence evolution r...

Zhichao Zhang, **aoyi Zhang, Yuan Tian, Liyuan Wang, **gting Cao… in Nature Communications (2024)

Article

COVID-19 was associated with the complications after allogeneic hematopoietic stem cell transplantation

We aimed to identify the severity and duration of COVID-19 infection on complications after allo-HSCT. Enrolled 179 hospitalized patients with COVID-19 were categorized into long-term infection (> 18 days, n = 90...

Qi Wen, Ze Guo, **ao-Hui Zhang, Lan-** Xu, Yu Wang, Chen-Hua Yan… in Scientific Reports (2024)

Article

Concentration-induced spontaneous polymerization of protic ionic liquids for efficient in situ adhesion

The advancement of contemporary adhesives is often limited by the balancing act between cohesion and interfacial adhesion strength. This study explores an approach to overcome this trade-off by utilizing the s...

Jun Zhang, Xuan Zhou, Qinyu Hu, Kaijian Zhou, Yan Zhang… in Nature Communications (2024)

Article

Three-dimensional liquid metal-based neuro-interfaces for human hippocampal organoids

Human hippocampal organoids (hHOs) derived from human induced pluripotent stem cells (hiPSCs) have emerged as promising models for investigating neurodegenerative disorders, such as schizophrenia and Alzheimer...

Yan Wu, **hao Cheng, Jie Qi, Chen Hang, Ruihua Dong… in Nature Communications (2024)

Article

A time-resolved multi-omics atlas of transcriptional regulation in response to high-altitude hypoxia across whole-body tissues

High-altitude hypoxia acclimatization requires whole-body physiological regulation in highland immigrants, but the underlying genetic mechanism has not been clarified. Here we use sheep as an animal model for ...

Ze Yan, Ji Yang, Wen-Tian Wei, Ming-Liang Zhou, Dong-**n Mo… in Nature Communications (2024)

Article

Initiating PeriCBD to probe perinatal influences on neurodevelopment during 3–10 years in China

Adverse perinatal factors can interfere with the normal development of the brain, potentially resulting in long-term effects on the comprehensive development of children. Presently, the understanding of cognit...

Yin-Shan Wang, Xue-Ting Su, Li Ke, Qing-Hua He, Da Chang, **g**g Nie… in Scientific Data (2024)

Article

Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion

The mechanisms of bifurcation, a key step in thyroid development, are largely unknown. Here we find three zebrafish lines from a forward genetic screening with similar thyroid dysgenesis phenotypes and identif...

Ya Fang, Jia-** Wan, Zheng Wang, Shi-Yang Song, Cao-Xu Zhang… in Nature Communications (2024)

Article

Author Correction: High quality assemblies of four indigenous chicken genomes and related functional data resources

Siwen Wu, Kun Wang, Tengfei Dou, Sisi Yuan, Shixiong Yan, Zhiqiang Xu… in Scientific Data (2024)

Article

Curcumin regulates autophagy through SIRT3-SOD2-ROS signaling pathway to improve quadriceps femoris muscle atrophy in KOA rat model

Knee osteoarthritis (KOA) usually leads to quadriceps femoris atrophy, which in turn can further aggravate the progression of KOA. Curcumin (CUR) has anti-inflammatory and antioxidant effects and has been show...

Hua Ye, Yi Long, Jia-Ming Yang, Yan-Lin Wu, Ling-Yan Dong… in Scientific Reports (2024)

Article

Author Correction: Cuproptosis-related genes predict prognosis and trastuzumab therapeutic response in HER2-positive breast cancer

Rui Sha, **nrui Dong, Shanshan Yan, Huijuan Dai, Aijun Sun… in Scientific Reports (2024)