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  1. Article

    Open Access

    Sodium tanshinone IIA sulfonate protects vascular relaxation in ApoE-knockout mice by inhibiting the SYK-NLRP3 inflammasome-MMP2/9 pathway

    Hyperlipidemia damages vascular wall and serves as a foundation for diseases such as atherosclerosis, hypertension and stiffness. The NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome is ...

    Hai-Hua Liu, Wei Wei, Fei-Fei Wu, Lu Cao, Bing-Jie Yang in BMC Cardiovascular Disorders (2024)

  2. Article

    Open Access

    Catheter ablation versus antiarrhythmic drug therapy for sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy

    Ventricular tachycardia (VT) is the primary cause of sudden cardiac death in patients with hypertrophic cardiomyopathy (HCM). However, the strategy for VT treatment in HCM patients remains unclear. This study ...

    Yan Dong, Xudong Song, Dan Bo, Hongtao Wang, Bo Yang in BMC Cardiovascular Disorders (2024)

  3. Article

    Open Access

    Identification through machine learning of potential immune- related gene biomarkers associated with immune cell infiltration in myocardial infarction

    To investigate the potential role of immune-related genes (IRGs) and immune cells in myocardial infarction (MI) and establish a nomogram model for diagnosing myocardial infarction.

    Hao Dong, Shi-Bai Yan, Guo-Sheng Li, Zhi-Guang Huang in BMC Cardiovascular Disorders (2023)

  4. Article

    Open Access

    Serum complement C1q level is associated with left ventricular hypertrophy induced by coarctation of the aorta: A retrospective observational study

    The complement system plays an important role in the development of left ventricular hypertrophy. Complement C1q is an initial component of the classical complement pathway and is related to many inflammatory ...

    Li Chen, Hong-zhou Duan, Chen Zhang, Gang Li, Yong-tao Wu in BMC Cardiovascular Disorders (2022)

  5. Article

    Open Access

    Clinical features of patients with septic shock-triggered Takotsubo syndrome: a single-center 7 case series

    Myocardial dysfunction is common in septic shock and has long been recognized. Takotsubo syndrome is an acute and usually reversible myocardial injury without evidence of an obstructive coronary artery disease...

    Chengqiao **g, Yan Wang, Chunmiao Kang, Daoran Dong in BMC Cardiovascular Disorders (2022)

  6. Article

    Open Access

    Clinical assessment and molecular mechanism of the upregulation of Toll-like receptor 2 (TLR2) in myocardial infarction

    The prevalence and mortality of cardiovascular diseases remain ranked first worldwide. Myocardial infarction (MI) is the central cause of death from cardiovascular diseases, seriously endangering human health....

    Ming-Jie Li, Shi-Bai Yan, Hao Dong, Zhi-Guang Huang in BMC Cardiovascular Disorders (2022)

  7. Article

    Open Access

    Combined effect of menopause and cardiovascular risk factors on death and cardiovascular disease: a cohort study

    Observational studies suggest that early menopause is associated with increased risk of death and cardiovascular disease (CVD); however, the results of these studies have been inconsistently. We aimed to asses...

    Yan Li, Dong Zhao, Miao Wang, Jia-yi Sun, Jun Liu, Yue Qi in BMC Cardiovascular Disorders (2021)

  8. Article

    Open Access

    Differential leukocyte counts and cardiovascular mortality in very old patients with acute myocardial infarction: a Chinese cohort study

    Total leukocyte and differential Leukocyte counts are prognostic indictors in patients with coronary artery disease (CAD). However, there is no data available regarding their prognostic utility in very old pat...

    **ao-Ni Yan, **g-Lu **, Meng Zhang, Li-Feng Hong in BMC Cardiovascular Disorders (2020)

  9. Article

    Open Access

    Lesion outline and thermal field distribution of ablative in vitro experiments in myocardia: comparison of radiofrequency and laser ablation

    To explore the lesion outline and thermal field distribution of radiofrequency ablation (RFA) and laser ablation (LA) in myocardial ablation in vitro.

    Wei Li, Jia Liu, Tong-yi Huang, **an Zhong, Dao-peng Yang in BMC Cardiovascular Disorders (2020)

  10. Article

    Open Access

    Revisiting right anterior oblique projections for the triangle of Koch: implications from computed tomography

    Variability in the anatomy and orientation of the triangle of Koch (TK) complicates ablation procedures involving the atrioventricular (AV) node. We used CT angiography (CTA) to assess the anatomical TK orient...

    Yan**g Wang, Lin Liu, Robert Lakin, Nazari Polidovitch in BMC Cardiovascular Disorders (2020)

  11. Article

    Open Access

    BMI differences among in-hospital management and outcomes in patients with atrial fibrillation: findings from the Care for Cardiovascular Disease project in China

    Underweight or obese status influences the prognosis of atrial fibrillation (AF). However, the association between stratification of body mass index (BMI) and in-hospital outcomes in patients with AF, remains ...

    Fuxue Deng, Yan Zhang, Qiang Zhao, Yangyang Deng in BMC Cardiovascular Disorders (2020)

  12. Article

    Open Access

    The important effect of 5-HTTLPR polymorphism on the risk of depression in patients with coronary heart disease: a meta-analysis

    Depression has been recognized as an independent risk factor of coronary heart disease (CHD). Moreover, there is interrelationship of both depression and CHD. However, the potential pathophysiological mechanis...

    Li-Jun Zhang, **an-Tao Zeng, Ming-Juan Zhao, Dong-Fang He in BMC Cardiovascular Disorders (2020)

  13. Article

    Open Access

    Predictive value of random blood glucose versus fasting blood glucose on in-hospital adverse events in patients with ST-segment elevation acute myocardial infarction

    We aim to find out the relationship between random blood glucose (RBG), fasting blood glucose (FBG) and in-hospital adverse events in ST-segment elevation acute myocardial infarction (STEMI) patients. We evalu...

    Yuhan Qin, Gaoliang Yan, Yong Qiao, Dong Wang, Erfei Luo in BMC Cardiovascular Disorders (2020)

  14. Article

    Open Access

    Risk factors of acute myocardial infarction in middle-aged and adolescent people (< 45 years) in Yantai

    Yantai is a developed medium-sized coastal city in Eastern China, having a population of 1.6845 million. With the development of economy, some middle-aged and adolescent people (< 45 years) devote themselves t...

    Hong Du, Chang-yan Dong, Qiao-yan Lin in BMC Cardiovascular Disorders (2015)