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  1. Article

    Open Access

    Ubiquitin-specific protease 22 is a deubiquitinase of CCNB1

    The elevated level of CCNB1 indicates more aggressive cancer and poor prognosis. However, the factors that cause CCNB1 upregulation remain enigmatic. Herein, we identify USP22 as a CCNB1 interactor and discove...

    Zhenghong Lin, Can Tan, Quan Qiu, Sinyi Kong, Heeyoung Yang, Fang Zhao in Cell Discovery (2015)

  2. Article

    Open Access

    A novel ER–microtubule-binding protein, ERLIN2, stabilizes Cyclin B1 and regulates cell cycle progression

    The gene encoding endoplasmic reticulum (ER) lipid raft-associated protein 2 (ERLIN2) is amplified in human breast cancers. ERLIN2 gene mutations were also found to be associated with human childhood progressive ...

    Xuebao Zhang, Juan Cai, Ze Zheng, Lisa Polin, Zhenghong Lin in Cell Discovery (2015)