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  1. Article

    Open Access

    Co-overexpression of geraniol-10-hydroxylase and strictosidine synthase improves anti-cancer drug camptothecin accumulation in Ophiorrhiza pumila

    Camptothecin (CPT) belongs to a group of monoterpenoidindole alkaloids (TIAs) and its derivatives such as irinothecan and topothecan have been widely used worldwide for the treatment of cancer, giving rise to ...

    Lijie Cui, **aoling Ni, Qian Ji, **aojuan Teng, Yanru Yang, Chao Wu… in Scientific Reports (2015)

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  2. No Access

    Article

    SNX13 reduction mediates heart failure through degradative sorting of apoptosis repressor with caspase recruitment domain

    Heart failure (HF) is associated with complicated molecular remodelling within cardiomyocytes; however, the mechanisms underlying this process remain unclear. Here we show that sorting nexin-13 (SNX13), a memb...

    Jun Li, Changming Li, Dasheng Zhang, Dan Shi, Man Qi, **g Feng… in Nature Communications (2014)