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Article
Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells
Fluorescent RNAs, aptamers that bind and activate small fluorogenic dyes, have provided a particularly attractive approach to visualizing RNAs in live cells. However, the simultaneous imaging of multiple RNAs ...
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Article
Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs
Fluorescent RNAs (FRs), aptamers that bind and activate fluorescent dyes, have been used to image abundant cellular RNA species. However, limitations such as low brightness and limited availability of dye/apta...
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Article
Open AccessAn effective approach for identification of in vivo protein-DNA binding sites from paired-end ChIP-Seq data
ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of protein-DNA interactions in vivo in the genome. H...