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Article
Open AccessAn Improved Method for Protein Similarity Searching by Alignment of Fuzzy Energy Signatures
Describing protein structures in terms of their energy features can be a key to understand how proteins work and interact to each other in cellular reactions. This can be also a base to compare proteins and se...
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Article
Open Accesssearch GenBank: interactive orchestration and ad-hoc choreography of Web services in the exploration of the biomedical resources of the National Center For Biotechnology Information
Due to the growing number of biomedical entries in data repositories of the National Center for Biotechnology Information (NCBI), it is difficult to collect, manage and process all of these entries in one plac...
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Article
Open AccessParallel implementation of 3D protein structure similarity searches using a GPU and the CUDA
Searching for similar 3D protein structures is one of the primary processes employed in the field of structural bioinformatics. However, the computational complexity of this process means that it is constantly...
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Article
Open AccessScaling Ab Initio Predictions of 3D Protein Structures in Microsoft Azure Cloud
Computational methods for protein structure prediction allow us to determine a three-dimensional structure of a protein based on its pure amino acid sequence. These methods are a very important alternative to ...
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Article
Open AccessAn efficient and flexible scanning of databases of protein secondary structures
Protein secondary structure describe protein construction in terms of regular spatial shapes, including alpha-helices, beta-strands, and loops, which protein amino acid chain can adopt in some of its regions. ...
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Article
Open AccessSpark-IDPP: high-throughput and scalable prediction of intrinsically disordered protein regions with Spark clusters on the Cloud
Intrinsically disorder proteins (IDPs) constitute a significant part of proteins that exist and act in cells of living organisms. IDPs play key roles in central cellular processes and some of them are closely ...
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Article
Open AccessHigh-throughput and scalable protein function identification with Hadoop and Map-only pattern of the MapReduce processing model
Efficient computational solutions for identification of protein functions or finding structural homologs of proteins gain importance in the era of structural genomics and in the face of growing volumes of biol...