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  1. Article

    Open Access

    An Improved Method for Protein Similarity Searching by Alignment of Fuzzy Energy Signatures

    Describing protein structures in terms of their energy features can be a key to understand how proteins work and interact to each other in cellular reactions. This can be also a base to compare proteins and se...

    Dariusz Mrozek, Bożena Małysiak-Mrozek in International Journal of Computational Int… (2011)

  2. Article

    Open Access

    search GenBank: interactive orchestration and ad-hoc choreography of Web services in the exploration of the biomedical resources of the National Center For Biotechnology Information

    Due to the growing number of biomedical entries in data repositories of the National Center for Biotechnology Information (NCBI), it is difficult to collect, manage and process all of these entries in one plac...

    Dariusz Mrozek, Bożena Małysiak-Mrozek, Artur Siążnik in BMC Bioinformatics (2013)

  3. Article

    Open Access

    Parallel implementation of 3D protein structure similarity searches using a GPU and the CUDA

    Searching for similar 3D protein structures is one of the primary processes employed in the field of structural bioinformatics. However, the computational complexity of this process means that it is constantly...

    Dariusz Mrozek, Miłosz Brożek, Bożena Małysiak-Mrozek in Journal of Molecular Modeling (2014)

  4. Article

    Open Access

    Scaling Ab Initio Predictions of 3D Protein Structures in Microsoft Azure Cloud

    Computational methods for protein structure prediction allow us to determine a three-dimensional structure of a protein based on its pure amino acid sequence. These methods are a very important alternative to ...

    Dariusz Mrozek, Paweł Gosk, Bożena Małysiak-Mrozek in Journal of Grid Computing (2015)

  5. Article

    Open Access

    An efficient and flexible scanning of databases of protein secondary structures

    Protein secondary structure describe protein construction in terms of regular spatial shapes, including alpha-helices, beta-strands, and loops, which protein amino acid chain can adopt in some of its regions. ...

    Dariusz Mrozek, Bartek Socha in Journal of Intelligent Information Systems (2016)

  6. Article

    Open Access

    Spark-IDPP: high-throughput and scalable prediction of intrinsically disordered protein regions with Spark clusters on the Cloud

    Intrinsically disorder proteins (IDPs) constitute a significant part of proteins that exist and act in cells of living organisms. IDPs play key roles in central cellular processes and some of them are closely ...

    Bożena Małysiak-Mrozek, Tomasz Baron, Dariusz Mrozek in Cluster Computing (2019)

  7. Article

    Open Access

    High-throughput and scalable protein function identification with Hadoop and Map-only pattern of the MapReduce processing model

    Efficient computational solutions for identification of protein functions or finding structural homologs of proteins gain importance in the era of structural genomics and in the face of growing volumes of biol...

    Dariusz Mrozek, Marek Suwała, Bożena Małysiak-Mrozek in Knowledge and Information Systems (2019)