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  1. No Access

    Article

    Incidence and course of Epstein-Barr virus viremia after allogeneic hematopoietic stem cell transplant for adult-onset systemic chronic active Epstein-Barr virus disease

    Preeti Prerna M. Vaswani, Masahiro Onozawa, Yuta Hasegawa in Bone Marrow Transplantation (2023)

  2. Article

    Open Access

    HokUS-10 scoring system predicts the treatment outcome for sinusoidal obstruction syndrome after allogeneic hematopoietic stem cell transplantation

    Hepatic sinusoidal obstruction syndrome (SOS) is a severe and life-threatening complication after allogeneic hematopoietic stem cell transplantation (HSCT). We conducted a multi-center retrospective study to e...

    Souichi Shiratori, Kohei Okada, Junichi Sugita, Mutsumi Nishida in Scientific Reports (2023)

  3. Article

    Open Access

    Decreased Paneth cell α-defensins promote fibrosis in a choline-deficient L-amino acid-defined high-fat diet-induced mouse model of nonalcoholic steatohepatitis via disrupting intestinal microbiota

    Nonalcoholic steatohepatitis (NASH) is a chronic liver disease characterized by fibrosis that develops from fatty liver. Disruption of intestinal microbiota homeostasis, dysbiosis, is associated with fibrosis ...

    Shunta Nakamura, Kiminori Nakamura, Yuki Yokoi, Yu Shimizu in Scientific Reports (2023)

  4. No Access

    Article

    Guest editorial: prophylaxis and treatment of relapse after allogeneic hematopoietic stem cell transplantation

    Daigo Hashimoto in International Journal of Hematology (2022)

  5. No Access

    Article

    Unilateral recurrent laryngeal nerve palsy detected by PET/CT in a patient with mediastinal T-cell lymphoblastic lymphoma

    Toru Miyajima, Yuta Hasegawa, Daigo Hashimoto in International Journal of Hematology (2022)

  6. Article

    Open Access

    High CRP-albumin ratio predicts poor prognosis in transplant ineligible elderly patients with newly diagnosed acute myeloid leukemia

    Acute myeloid leukemia (AML) patients older than 65 years have a poor prognosis. Recently, CAR (C-reactive-protein/albumin ratio) has been actively reported as a prognostic index reflecting the nutritional and...

    Hajime Senjo, Masahiro Onozawa, Daisuke Hidaka, Shota Yokoyama in Scientific Reports (2022)

  7. No Access

    Article

    Gilteritinib enhances graft-versus-leukemia effects against FLT3-ITD mutant leukemia after allogeneic hematopoietic stem cell transplantation

    Allogeneic hematopoietic stem cell transplantation (allo-SCT) is a potentially curative therapy for FLT3 internal tandem duplication mutant (FLT3-ITD+) acute myeloid leukemia, but relapse rate is high. A recent s...

    Zixuan Zhang, Yuta Hasegawa, Daigo Hashimoto, Hajime Senjo in Bone Marrow Transplantation (2022)

  8. No Access

    Article

    Low-dose antithymocyte globulin inhibits chronic graft-versus-host disease in peripheral blood stem cell transplantation from unrelated donors

    Antithymocyte globulin (ATG) has been shown to reduce chronic graft-versus-host disease (GVHD) particularly in allogeneic peripheral blood stem cell transplantation (PBSCT) from unrelated donors; however, anti...

    Souichi Shiratori, Junichi Sugita, Shigeo Fuji, Jun Aoki in Bone Marrow Transplantation (2021)

  9. No Access

    Article

    High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease

    Antithymocyte globulin (ATG) reduces severe acute and chronic graft-versus-host disease (GVHD) in allogeneic peripheral blood stem cell transplantation (PBSCT). However, risk factors for severe acute GVHD in P...

    Souichi Shiratori, Hiroyuki Ohigashi, Takahide Ara in Annals of Hematology (2021)

  10. No Access

    Article

    Extramedullary hematopoiesis of the cranial dura

    Keito Suto, Junichi Sugita, Daigo Hashimoto in International Journal of Hematology (2021)

  11. No Access

    Article

    Validation and comparison of prognostic values of GNRI, PNI, and CONUT in newly diagnosed diffuse large B cell lymphoma

    Diffuse large B cell lymphoma (DLBCL) is the most common type of aggressive non-Hodgkin lymphoma. Emerging evidence indicates that poor nutritional status determined with nutritional indices such as geriatric ...

    Toshihiro Matsukawa, Keito Suto, Minoru Kanaya, Koh Izumiyama in Annals of Hematology (2020)

  12. Article

    Open Access

    A novel nutritional index “simplified CONUT” and the disease risk index independently stratify prognosis of elderly patients with acute myeloid leukemia

    Elderly patients aged 65 or older with acute myeloid leukemia (AML) have poor prognosis. The risk stratification based on genetic alteration has been proposed in national comprehensive cancer network (NCCN) gu...

    Hajime Senjo, Masahiro Onozawa, Daisuke Hidaka, Shota Yokoyama in Scientific Reports (2020)

  13. No Access

    Article

    Histological and magnified endoscopic evaluation of villous atrophy in gastrointestinal graft-versus-host disease

    Aim: To measure histological villous atrophy and to clarify the diagnostic accuracy of endoscopic villous atrophy in gastrointestinal graft-versus-host disease. Methods: Data for patients who underwent upper a...

    Kana Matsuda, Shoko Ono, Ikko Tanaka, Masaki Inoue, Sayoko Kinowaki in Annals of Hematology (2020)

  14. No Access

    Article

    Short-term KRP203 and posttransplant cyclophosphamide for graft-versus-host disease prophylaxis

    Posttransplant high-dose cyclophosphamide (PTCY) has been increasingly used as graft-versus-host disease (GVHD) prophylaxis after HLA-haploidentical or matched hematopoietic stem cell transplantation (SCT). Ho...

    Emi Yokoyama, Daigo Hashimoto, Eiko Hayase, Takahide Ara in Bone Marrow Transplantation (2020)

  15. No Access

    Article

    Reduced dose of MTX for GVHD prophylaxis promotes engraftment and decreases non-relapse mortality in umbilical cord blood transplantation

    Although a combination of calcineurin inhibitor and methotrexate (MTX) is used for graft-versus-host disease (GVHD) prophylaxis in umbilical cord blood transplantation (CBT), optimal dose of MTX for CBT remain...

    Souichi Shiratori, Hiroyuki Ohigashi, Shuichiro Takahashi in Annals of Hematology (2020)

  16. No Access

    Article

    Loss of nivolumab binding to T cell PD-1 predicts relapse of Hodgkin lymphoma

    Nivolumab is effective in the treatment of classical Hodgkin lymphoma that relapsed after allogeneic hematopoietic stem cell transplantation (SCT) with the risk of graft-versus-host disease; however, the optim...

    Reiki Ogasawara, Daigo Hashimoto, Junichi Sugita in International Journal of Hematology (2020)

  17. No Access

    Article

    Unusual computed tomography findings of acute eosinophilic pneumonia after cord blood transplantation

    Hajime Senjo, Daigo Hashimoto in International Journal of Hematology (2019)

  18. Article

    Open Access

    Intestinal Lymphatic Endothelial Cells Produce R-Spondin3

    The R-Spondin (R-Spo) family regulates WNT signaling and stimulates the proliferation and differentiation of intestinal stem cells (ISCs). R-Spo plays a critical role in maintaining intestinal homeostasis, but...

    Reiki Ogasawara, Daigo Hashimoto, Shunsuke Kimura, Eiko Hayase in Scientific Reports (2018)

  19. No Access

    Article

    Cecum ulcer is a reliable endoscopic finding in cytomegalovirus colitis concomitant with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

    Although graft-versus-host disease (GVHD) is the major complication of allogeneic hematopoietic stem cell transplantation (allo-HSCT), cytomegalovirus (CMV) reactivation also occurs in patients after allo-HSCT...

    Kana Matsuda, Shoko Ono, Marin Ishikawa, Shuichi Miyamoto in Annals of Hematology (2018)

  20. No Access

    Article

    A novel heterozygous ITGB3 p.T720del inducing spontaneous activation of integrin αIIbβ3 in autosomal dominant macrothrombocytopenia with aggregation dysfunction

    We identified a novel heterozygous ITGB3 p.T720del mutation in a pedigree with macrothrombocytopenia exhibiting aggregation dysfunction. Platelet aggregation induced by ADP and collagen was significantly reduced,...

    Naohiro Miyashita, Masahiro Onozawa, Koji Hayasaka, Takahiro Yamada in Annals of Hematology (2018)

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