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Article
Macromolecular structures probed by combining single-shot free-electron laser diffraction with synchrotron coherent X-ray imaging
Nanostructures formed from biological macromolecular complexes utilizing the self-assembly properties of smaller building blocks such as DNA and RNA hold promise for many applications, including sensing and dr...
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Article
Single-shot three-dimensional structure determination of nanocrystals with femtosecond X-ray free-electron laser pulses
Conventional three-dimensional (3D) structure determination methods require either multiple measurements at different sample orientations or a collection of serial sections through a sample. Here we report the...
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Article
Open AccessCoherent diffraction of single Rice Dwarf virus particles using hard X-rays at the Linac Coherent Light Source
Single particle diffractive imaging data from Rice Dwarf Virus (RDV) were recorded using the Coherent X-ray Imaging (CXI) instrument at the Linac Coherent Light Source (LCLS). RDV was chosen as it is a well-ch...
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Article
Open AccessVisualization of a Mammalian Mitochondrion by Coherent X-ray Diffractive Imaging
We report a three dimensional (3D) quantitative visualization of a mammalian mitochondrion by coherent x-ray diffractive imaging (CXDI) using synchrotron radiation. The internal structures of a mitochondrion f...
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Article
Open AccessCoherent soft X-ray diffraction imaging of coliphage PR772 at the Linac coherent light source
Single-particle diffraction from X-ray Free Electron Lasers offers the potential for molecular structure determination without the need for crystallization. In an effort to further develop the technique, we pr...
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Article
Open AccessSingle-shot 3D coherent diffractive imaging of core-shell nanoparticles with elemental specificity
We report 3D coherent diffractive imaging (CDI) of Au/Pd core-shell nanoparticles with 6.1 nm spatial resolution with elemental specificity. We measured single-shot diffraction patterns of the nanoparticles us...
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Article
Open AccessCoherence and pulse duration characterization of the PAL-XFEL in the hard X-ray regime
We characterize the spatial and temporal coherence properties of hard X-ray pulses from the Pohang Accelerator Laboratory X-ray Free Electron Laser (PAL-XFEL, Pohang, Korea). The measurement of the single-shot...
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Article
Open AccessDirect observation of picosecond melting and disintegration of metallic nanoparticles
Despite more than a century of study, the fundamental mechanisms behind solid melting remain elusive at the nanoscale. Ultrafast phenomena in materials irradiated by intense femtosecond laser pulses have reviv...
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Article
Open AccessSimultaneous bright- and dark-field X-ray microscopy at X-ray free electron lasers
The structures, strain fields, and defect distributions in solid materials underlie the mechanical and physical properties across numerous applications. Many modern microstructural microscopy tools characteriz...