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Inhibition of homodimerization of toll-like receptor 4 by (E)-isopropyl 4-oxo-4-(2-oxopyrrolidin-1-yl)-2-butenoate

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  1. Article

    Open Access

    Sulforaphane attenuates pulmonary fibrosis by inhibiting the epithelial-mesenchymal transition

    Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal disease with no effective treatment. The epithelial-mesenchymal transition (EMT) is a critical stage during the development of fibrosis. To assess...

    Sun Young Kyung, Dae Young Kim, ** Young Yoon… in BMC Pharmacology and Toxicology (2018)

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  2. Article

    Open Access

    High susceptibility of metastatic cells derived from human prostate and colon cancer cells to TRAIL and sensitization of TRAIL-insensitive primary cells to TRAIL by 4,5-dimethoxy-2-nitrobenzaldehyde

    Tumor recurrence and metastasis develop as a result of tumors' acquisition of anti-apoptotic mechanisms and therefore, it is necessary to develop novel effective therapeutics against metastatic cancers. In thi...

    Hak-Bong Kim, Mi-Ju Kim, Dae-Young Kim, Jae-Won Lee, Jae-Ho Bae… in Molecular Cancer (2011)

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  3. Article

    Open Access

    Release of heat shock protein 70 (Hsp70) and the effects of extracellular Hsp70 on matric metalloproteinase-9 expression in human monocytic U937 cells

    Heat shock protein 70 (Hsp70) release and its effects on pro-inflammatory cytokine production have been controversial. In this study, we investigated whether Hsp70 could be released from monocytes and activate...

    Kyoung-** Lee, Yoo Mih Kim, Dae Young Kim… in Experimental & Molecular Medicine (2006)

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