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  1. Article

    Correction: Biomimetic Antidote Nanoparticles: A Novel Strategy for Chronic Heavy Metal Poisoning

    Hao Wang, Qing Yao, Wenquan Zhu, Yang Yang, Chunsheng Gao… in AAPS PharmSciTech (2023)

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  2. Article

    Open Access

    Efficacy and Safety of Denosumab Biosimilar QL1206 Versus Denosumab in Patients with Bone Metastases from Solid Tumors: A Randomized Phase III Trial

    Denosumab has been approved for the treatment of bone metastases from solid tumors. QL1206 is the first denosumab biosimilar and needs to be compared with denosumab in a phase III trial.

    Hui** Li, Yan Huang, Zhendong Chen, Ai** Zeng, Helong Zhang, Yan Yu… in BioDrugs (2023)

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    Article

    A phase III randomized, double-blind, placebo-controlled trial of the denosumab biosimilar QL1206 in postmenopausal Chinese women with osteoporosis and high fracture risk

    The current study evaluated the efficacy and safety of a denosumab biosimilar, QL1206 (60 mg), compared to placebo in postmenopausal Chinese women with osteoporosis and high fracture risk. At 31 study centers ...

    Hao Zhang, Jie-mei Gu, Ai-jun Chao, Qun Cheng, Dong-hui Teng… in Acta Pharmacologica Sinica (2023)

  4. No Access

    Article

    Biomimetic Antidote Nanoparticles: a Novel Strategy for Chronic Heavy Metal Poisoning

    Chronic lead poisoning has become a major factor in global public health. Chelation therapy is usually used to manage lead poisoning. Dimercaptosuccinic acid (DMSA) is a widely used heavy metal chelation agent...

    Hao Wang, Qing Yao, Wenquan Zhu, Yang Yang, Chunsheng Gao, Cuiyan Han… in AAPS PharmSciTech (2022)

  5. Article

    Open Access

    ANP32A dysregulation contributes to abnormal megakaryopoiesis in acute megakaryoblastic leukemia

    Xueqin Sun, Bin Lu, Cuijuan Han, Wanlin Qiu, Qi **, Dengju Li… in Blood Cancer Journal (2017)

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  6. Article

    Dipyrithione inhibits IFN-γ-induced JAK/STAT1 signaling pathway activation and IP-10/CXCL10 expression in RAW264.7 cells

    This study investigates the effects of dipyrithione (PTS2) on the expression of IP-10/CXCL10, which has been observed in a wide variety of chronic inflammatory disorders and autoimmune conditions.

    Cui Han, ** Fu, Ziwen Liu, Huang Huang, Lan Luo, Zhimin Yin in Inflammation Research (2010)

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  7. No Access

    Article

    Heat shock protein 70 together with its co-chaperone CHIP inhibits TNF-α induced apoptosis by promoting proteasomal degradation of apoptosis signal-regulating kinase1

    Inducible heat shock protein70 (HSP70) is one of the most important HSPs for maintenance of cell integrity during normal cellular growth as well as pathophysiological conditions. Apoptosis signal-regulating ki...

    Yanhong Gao, Cui Han, Huang Huang, Yinqiang **n, Yimiao Xu, Lan Luo… in Apoptosis (2010)