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4-1BB signaling activates glucose and fatty acid metabolism to enhance CD8+ T cell proliferation

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  1. Article

    Open Access

    4-1BB-4-1BBL cis-interaction contributes to the survival of self-reactive CD8+ T cell

    Eunjung Cho, Rohit Singh, Chungyong Han, Seon-Hee Kim… in Cellular & Molecular Immunology (2023)

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  2. Article

    Open Access

    Chronic activation of 4-1BB signaling induces granuloma development in tumor-draining lymph nodes that is detrimental to subsequent CD8+ T cell responses

    The antitumor capabilities of agonistic anti-4-1BB mAbs have made them an attractive target for tumor immunotherapy. However, the adverse side effects associated with agonist antibodies have hindered their cli...

    Seon-Hee Kim, Rohit Singh, Chungyong Han, Eunjung Cho… in Cellular & Molecular Immunology (2021)

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