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  1. No Access

    Article

    ARMc8 indicates aggressive colon cancers and promotes invasiveness and migration of colon cancer cells

    Recent studies have implicated ARMc8 in promoting tumor formation in non-small cell lung cancer and breast cancer; however, so far, no studies have revealed the expression pattern or cellular function of ARMc8...

    Guiyang Jiang, Yong Zhang, **upeng Zhang, Chuifeng Fan, Liang Wang… in Tumor Biology (2015)

  2. No Access

    Article

    A novel biomarker C6orf106 promotes the malignant progression of breast cancer

    C6orf106 (chromosome 6 open reading frame 106) is a recently discovered protein encoded by the 6th chromosome. Though many proteins encoded by chromosome 6 are reportedly related to cancer, schizophrenia, auto...

    Guiyang Jiang, **upeng Zhang, Yong Zhang, Liang Wang, Chuifeng Fan… in Tumor Biology (2015)

  3. No Access

    Article

    Armc8 expression was elevated during atypia-to-carcinoma progression and associated with cancer development of breast carcinoma

    Armadillo repeat-containing protein 8 (Armc8) is a key factor to regulate cell membrane adhesion complex through promoting α-catenin degradation. However, its expression and function in human malignant tumors ...

    Chuifeng Fan, Yang Zhao, **aoyun Mao, Yuan Miao, Xuyong Lin, Guiyang Jiang… in Tumor Biology (2014)

  4. Article

    Open Access

    Btbd7 contributes to reduced E-cadherin expression and predicts poor prognosis in non-small cell lung cancer

    Disorders of cell adhesion are critical steps in cancer progression in which varieties of markers including cadherins are involved in.Btbd7 was found to inhibit E-cadherin expression in MDCK cells and play imp...

    Chuifeng Fan, Yuan Miao, **upeng Zhang, Di Liu, Guiyang Jiang, Xuyong Lin… in BMC Cancer (2014)

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  5. No Access

    Article

    ARMC8α promotes proliferation and invasion of non-small cell lung cancer cells by activating the canonical Wnt signaling pathway

    ARMC8 proteins are novel armadillo repeat containing proteins, which are well conserved in eukaryotes and are involved in a variety of processes such as cell migration, proliferation, tissue maintenance, signa...

    Chengyao **e, Guiyang Jiang, Chuifeng Fan, **upeng Zhang, Yong Zhang… in Tumor Biology (2014)

  6. Article

    Open Access

    CXCL12-CXCR4 axis promotes the natural selection of breast cancer cell metastasis

    CXCR4 and its ligand CXCL12 can promote the proliferation, survival, and invasion of cancer cells. They have been shown to play an important role in regulating metastasis of breast cancer to specific organs. H...

    Yanan Sun, **aoyun Mao, Chuifeng Fan, Chong Liu, Ayao Guo, Shu Guan… in Tumor Biology (2014)

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  7. No Access

    Article

    ASAP3 expression in non-small cell lung cancer: association with cancer development and patients’ clinical outcome

    ASAP3 belongs to Arf-specific GTPase-activating proteins which regulate Arfs by stimulating their intrinsic GTP hydrolysis. ASAP3 expression and the clinical significance in malignant tumors are largely unknow...

    Chuifeng Fan, Yuan Tian, Yuan Miao, Xuyong Lin, **upeng Zhang… in Tumor Biology (2014)

  8. No Access

    Article

    Clinicopathological significance of cathepsin D expression in non-small cell lung cancer is conditional on apoptosis-associated protein phenotype: an immunohistochemistry study

    Cathepsin D is a well-known peptidase which belongs to the family of aspartic peptidases. It has been found to be overexpressed in many malignant tumors and associated with cancer metastasis and clinical outco...

    Chuifeng Fan, Xuyong Lin, Enhua Wang in Tumor Biology (2012)

  9. No Access

    Article

    Increased NDRG1 Expression is Associated with Advanced T Stages and Poor Vascularization in Non-small Cell Lung Cancer

    N-myc downstream regulated gene 1 (NDRG1) is a member of the N-myc downstream regulated gene family which belongs to the alpha/beta hydrolase superfamily. Earlier studies have shown its association with inhibi...

    Chuifeng Fan, Juanhan Yu, Yang Liu, Hongtao Xu, Enhua Wang in Pathology & Oncology Research (2012)

  10. No Access

    Article

    Detection of Brk expression in non-small cell lung cancer: clinicopathological relevance

    Breast tumor kinase (Brk), also known as protein tyrosine kinase 6, is a nonreceptor tyrosine kinase containing SH3, SH2, and tyrosine kinase catalytic domains. Brk upregulation and oncogenic properties have b...

    Chuifeng Fan, Yang Zhao, Di Liu, **upeng Zhang, Enhua Wang in Tumor Biology (2011)