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Open AccessAXL is a potential therapeutic target in dedifferentiated and pleomorphic liposarcomas
AXL is a well-characterized, protumorigenic receptor tyrosine kinase that is highly expressed and activated in numerous human carcinomas and sarcomas, including aggressive subtypes of liposarcoma. However, the...
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Article
Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
Aberrant activation of a latent embryonic program - known as the epithelial-mesenchymal transition (EMT) - can endow cancer cells with the migratory and invasive capabilities associated with metastatic compete...