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Open AccessThe effect of salt substitution on frequency and severity of headache: results from the SSaSS cluster-randomised controlled trial of 20,995 participants
Headache is one of the most common neurological symptoms. Headache disorders are associated with a high global burden of disease. Prior studies indicate that short-to-medium term sodium reduction reduces heada...
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Open AccessThe contribution of sodium reduction and potassium increase to the blood pressure lowering observed in the Salt Substitute and Stroke Study
The Salt Substitute and Stroke Study (SSaSS) demonstrated significant reductions in systolic blood pressure (SBP), and the risk of stroke, major cardiovascular events and total mortality with the use of potass...
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Article
Open AccessFactors influencing the time to ethics and governance approvals for clinical trials: a retrospective cross-sectional survey
The findings from multi-centre trials are central to the practice of evidence-based medicine, enabling the development and implementation of new treatments. The time it takes to commence clinical trials at sit...
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Open Access2022 World Hypertension League, Resolve To Save Lives and International Society of Hypertension dietary sodium (salt) global call to action
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Open AccessProtocol for the Metformin Aneurysm Trial (MAT): a placebo-controlled randomised trial testing whether metformin reduces the risk of serious complications of abdominal aortic aneurysm
Multiple observational studies have associated metformin prescription with reduced progression of abdominal aortic aneurysm (AAA). The Metformin Aneurysm Trial (MAT) will test whether metformin reduces the ris...
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The impact of baseline potassium intake on the dose–response relation between sodium reduction and blood pressure change: systematic review and meta-analysis of randomized trials
Sodium and potassium appear to interact with each other in their effects on blood pressure with potassium supplementation having a greater blood pressure lowering-effect when sodium intake is high. Whether the...
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Article
Is salt substitution ready for prime time?
Salt substitutes hold great potential for the control of blood pressure and prevention of chronic disease, but the evidence base remains inadequate. Data from a community-based trial in Peru add to this eviden...
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Open AccessDoes education level affect the efficacy of a community based salt reduction program? - A post-hoc analysis of the China Rural Health Initiative Sodium Reduction Study (CRHI-SRS)
Whether educational level influences the effects of health education is not clearly defined. This study examined whether the impact of a community-based dietary salt reduction program was affected by the level...
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Open AccessDesigning a Healthy Food Partnership: lessons from the Australian Food and Health Dialogue
Poor diets are a leading cause of disease burden worldwide. In Australia, the Federal Government established the Food and Health Dialogue (the Dialogue) in 2009 to address this issue, primarily through food re...
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Open AccessEffects of a community-based salt reduction program in a regional Australian population
Salt reduction is a public health priority but there are few studies testing the efficacy of plausible salt reduction programs.
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Open AccessProtocol for a cluster-randomised trial to determine the effects of advocacy actions on the salt content of processed foods
Corporate decisions affecting the composition of processed foods are a potent factor sha** the nutritional quality of the food supply. The addition of large quantities of salt to foods is incompatible with A...
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Article
Open AccessA shortened verbal autopsy instrument for use in routine mortality surveillance systems
Verbal autopsy (VA) is recognized as the only feasible alternative to comprehensive medical certification of deaths in settings with no or unreliable vital registration systems. However, a barrier to its use b...
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Open AccessImproving performance of the Tariff Method for assigning causes of death to verbal autopsies
Reliable data on the distribution of causes of death (COD) in a population are fundamental to good public health practice. In the absence of comprehensive medical certification of deaths, the only feasible way...
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Article
The Influence on Population Weight Gain and Obesity of the Macronutrient Composition and Energy Density of the Food Supply
Rates of overweight and obesity have increased dramatically in all regions of the world over the last few decades. Almost all of the world’s population now has ubiquitous access to low-cost, but highly-process...
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Open AccessEffects of interpretive front-of-pack nutrition labels on food purchases: protocol for the Starlight randomised controlled trial
Interpretive front-of-pack nutrition labels are better understood than non-interpretive labels. However, robust evidence on the effects of such labels on consumer food purchases in the real-world is lacking. O...
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Open AccessUsing mobile technology to support lower-salt food choices for people with cardiovascular disease: protocol for the SaltSwitch randomized controlled trial
Cardiovascular disease (CVD) is the leading cause of early death worldwide, responsible for an estimated 29% of all global deaths. Reducing salt intake lowers blood pressure and risk of secondary cardiac event...
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Open AccessProtocol for the implementation and evaluation of a community-based intervention seeking to reduce dietary salt intake in Lithgow, Australia
Excess dietary salt is a leading risk for health. Multiple health, government, industry and community organisations have identified the need to reduce consumption of dietary salt. This project seeks to impleme...
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Open AccessPopulation impact of a high cardiovascular risk management program delivered by village doctors in rural China: design and rationale of a large, cluster-randomized controlled trial
The high-risk strategy has been proven effective in preventing cardiovascular disease; however, the population benefits from these interventions remain unknown. This study aims to assess, at the population lev...
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Open AccessCost-effectiveness of reducing salt intake in the Pacific Islands: protocol for a before and after intervention study
There is broad consensus that diets high in salt are bad for health and that reducing salt intake is a cost-effective strategy for preventing chronic diseases. The World Health Organization has been supporting...
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Open AccessUsing verbal autopsy to measure causes of death: the comparative performance of existing methods
Monitoring progress with disease and injury reduction in many populations will require widespread use of verbal autopsy (VA). Multiple methods have been developed for assigning cause of death from a VA but the...