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Article
Open AccessIGF2 deficiency promotes liver aging through mitochondrial dysfunction and upregulated CEBPB signaling in d-galactose-induced aging mice
Liver aging, marked by cellular senescence and low-grade inflammation, heightens susceptibility to chronic liver disease and worsens its prognosis. Insulin-like growth factor 2 (IGF2) has been implicated in nu...
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Article
Open AccessRestorative biodegradable two-layered hybrid microneedles for melanoma photothermal/chemo co-therapy and wound healing
Tumor killing and wound healing are two complementary and influential processes during the treatment of melanoma. Herein, a two-layered microneedle platform was developed with bifunctional effect of chemo-phot...
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Article
Open AccessPhotothermal hydrogel platform for prevention of post-surgical tumor recurrence and improving breast reconstruction
As one of the leading threats for health among women worldwide, breast cancer has high morbidity and mortality. Surgical resection is the major clinical intervention for primary breast tumor, nevertheless high...
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Article
Open AccessBiomaterial-based strategies for maxillofacial tumour therapy and bone defect regeneration
Issues caused by maxillofacial tumours involve not only dealing with tumours but also repairing jaw bone defects. In traditional tumour therapy, the systemic toxicity of chemotherapeutic drugs, invasive surgic...
