8 Result(s)
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Article
Low-dose Methotrexate Inhibits Lung Metastasis and Lengthens Survival in Rat Osteosarcoma
Lung metastasis is the most crucial event affecting the treatment of osteosarcoma and is dependent on tumor angiogenesis. To improve the prognosis for patients with osteosarcoma, prevention of lung metastasis ...
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Article
Novel hyperthermia for metastatic bone tumors with magnetic materials by generating an alternating electromagnetic field
We have developed a novel hyperthermic treatment modality using magnetic materials for metastatic bone tumors. The purpose of this study is to show the results of novel hyperthermia for metastatic bone tumors....
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Article
Open AccessIntradural squamous cell carcinoma in the sacrum
Leptomeningeal carcinomatosis occurs in patients with cancer at the rate of approximately 5%; it develops particularly in patients with breast cancer, lung cancer, melanoma, leukemia, or malignant lymphoma. We...
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Article
Management of small pulmonary nodules in patients with sarcoma
Small pulmonary nodules in patients with sarcoma are problematic, because it is difficult to distinguish such small metastatic nodules from benign. The purpose of this study was to establish management guideli...
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Article
A novel hyperthermia treatment for bone metastases using magnetic materials
Patients with bone metastases in the extremities sometimes require surgical intervention to prevent deterioration of quality of life due to a pathological fracture. The use of localized radiotherapy combined w...
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Article
Open AccessThe adverse effect of an unplanned surgical excision of foot soft tissue sarcoma
Malignant soft tissue tumors of the foot are extremely rare and thus can be prematurely excised without appropriate preoperative evaluation. The present study compares adverse effects between unplanned and pla...
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Article
Open AccessSoluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors
Neural-cadherin (N-cadherin) is one of the most important molecules involved in tissue morphogenesis, wound healing, and the maintenance of tissue integrity. Recently, the cleavage of N-cadherin has become a f...
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Article
The thrombin inhibitor, argatroban, inhibits breast cancer metastasis to bone
Breast cancer has the potential to metastasize to bone, causing debilitating symptoms. Although many tumor cells have thrombin-generating systems originating from tissue factor (TF), therapy in terms of the co...
