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  1. Article

    Open Access

    Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors

    Neural-cadherin (N-cadherin) is one of the most important molecules involved in tissue morphogenesis, wound healing, and the maintenance of tissue integrity. Recently, the cleavage of N-cadherin has become a f...

    Rui Niimi, Akihiko Matsumine, Takahiro Iino, Shigeto Nakazora… in BMC Cancer (2013)

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    Article

    Management of small pulmonary nodules in patients with sarcoma

    Small pulmonary nodules in patients with sarcoma are problematic, because it is difficult to distinguish such small metastatic nodules from benign. The purpose of this study was to establish management guideli...

    Tomoki Nakamura, Akihiko Matsumine, Rui Niimi… in Clinical & Experimental Metastasis (2009)

  3. No Access

    Article

    Novel hyperthermia for metastatic bone tumors with magnetic materials by generating an alternating electromagnetic field

    We have developed a novel hyperthermic treatment modality using magnetic materials for metastatic bone tumors. The purpose of this study is to show the results of novel hyperthermia for metastatic bone tumors....

    Akihiko Matsumine, Katsuyuki Kusuzaki… in Clinical & Experimental Metastasis (2007)

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    Article

    Low-dose Methotrexate Inhibits Lung Metastasis and Lengthens Survival in Rat Osteosarcoma

    Lung metastasis is the most crucial event affecting the treatment of osteosarcoma and is dependent on tumor angiogenesis. To improve the prognosis for patients with osteosarcoma, prevention of lung metastasis ...

    Ryota Tomoda, Masashi Seto, Yasunari Hioki… in Clinical & Experimental Metastasis (2005)