2 Result(s)
within
Life Sciences
Biochemistry, general
Andrew Hall
Article
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Article
Open AccessComputational approaches identify a transcriptomic fingerprint of drug-induced structural cardiotoxicity
Structural cardiotoxicity (SCT) presents a high-impact risk that is poorly tolerated in drug discovery unless significant benefit is anticipated. Therefore, we aimed to improve the mechanistic understanding of...
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Article
Open AccessThe endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells
Fatty acid uptake and metabolism are often dysregulated in cancer cells. Fatty acid activation is a critical step that allows these biomolecules to enter cellular metabolic pathways such as mitochondrial β-oxi...
