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    Article

    Revisiting the role of glucagon in health, diabetes mellitus and other metabolic diseases

    Insulin and glucagon exert opposing effects on glucose metabolism and, consequently, pancreatic islet β-cells and α-cells are considered functional antagonists. The intra-islet hypothesis has previously domina...

    Sofie Hædersdal, Andreas Andersen, Filip K. Knop… in Nature Reviews Endocrinology (2023)

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    Article

    Glucagon-like peptide 1 in health and disease

    In healthy individuals, the incretin hormone glucagon-like peptide 1 (GLP1) potentiates insulin release and suppresses glucagon secretion in response to the ingestion of nutrients. GLP1 also delays gastric emp...

    Andreas Andersen, Asger Lund, Filip K. Knop, Tina Vilsbøll in Nature Reviews Endocrinology (2018)