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Article
Perspectives from the Society for Pediatric Research. Neonatal encephalopathy clinical trials: develo** the future
The next phase of clinical trials in neonatal encephalopathy (NE) focuses on hypothermia adjuvant therapies targeting alternative recovery mechanisms during the process of hypoxic brain injury. Identifying inf...
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Article
Placental pathology and neonatal brain MRI in a randomized trial of erythropoietin for hypoxic–ischemic encephalopathy
Newborns with hypoxic–ischemic encephalopathy (HIE) may exhibit abnormalities on placental histology. In this phase II clinical trial ancillary study, we hypothesized that placental abnormalities correlate wit...
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Article
Open AccessCluster headache attack remission with sphenopalatine ganglion stimulation: experiences in chronic cluster headache patients through 24 months
Cluster headache (CH) is a debilitating headache disorder with severe consequences for patient quality of life. On-demand neuromodulation targeting the sphenopalatine ganglion (SPG) is effective in treating th...
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Article
Open AccessResults of a patient survey for an implantable neurostimulator to treat migraine headaches
Migraine attacks are believed to involve activation of the trigeminovascular system and trigeminal-parasympathetic reflex, which is mediated through the sphenopalatine ganglion (SPG). An implantable SPG neuros...
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Article
Minimum Energy Single-Shock Internal Atrial Defibrillation in Sheep
Well-tolerated internal atrial defibrillation shocks must be below the pain threshold, which has been estimated to be less than 1 Joule. Defibrillation of the atria with low energy is made possible by deliveri...