5 Result(s)

Article

Author Correction: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration

Sarah Opie-Martin, Alfredo Iacoangeli, Simon D. Topp… in Nature Communications (2024)

Article

The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration

Superoxide dismutase (SOD1) gene variants may cause amyotrophic lateral sclerosis, some of which are associated with a distinct phenotype. Most studies assess limited variants or sample sizes. In this internation...

Sarah Opie-Martin, Alfredo Iacoangeli, Simon D. Topp… in Nature Communications (2022)

Article

Author Correction: A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex

Ashley R. Jones, Alfredo Iacoangeli, Brett N. Adey, Harry Bowles… in Scientific Reports (2022)

Article

Amyotrophic lateral sclerosis and cerebellum

Amyotrophic lateral sclerosis (ALS) is a devastating, heterogeneous neurodegenerative neuromuscular disease that leads to a fatal outcome within 2–5 years, and yet, a precise nature of the association between ...

Renata Kabiljo, Alfredo Iacoangeli, Ammar Al-Chalabi… in Scientific Reports (2022)

Article

A HML6 endogenous retrovirus on chromosome 3 is upregulated in amyotrophic lateral sclerosis motor cortex

There is increasing evidence that endogenous retroviruses (ERVs) play a significant role in central nervous system diseases, including amyotrophic lateral sclerosis (ALS). Studies of ALS have consistently iden...

Ashley R. Jones, Alfredo Iacoangeli, Brett N. Adey, Harry Bowles… in Scientific Reports (2021)