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Article
Open AccessKIF22 promotes multiple myeloma progression by regulating the CDC25C/CDK1/cyclinB1 pathway
Multiple myeloma (MM) is an incurable hematological malignancy characterized by clonal proliferation of malignant plasma B cells in bone marrow, and its pathogenesis remains unknown. The aim of this study was ...
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Article
Open AccessPan-cancer analysis of DDIT4 identifying its prognostic value and function in acute myeloid leukemia
Acute myeloid leukemia (AML) is a hematological malignancy derived from the accumulation of abnormal proliferation of infantile leukocytes in the hematopoietic system. DNA-damage-inducible transcript 4 (DDIT4) ac...
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Article
Novel insights into roles of N6-methyladenosine reader YTHDF2 in cancer progression
N6-methyladenosine (m6A) is the most abundant RNA modification. M6A RNA methylation is reversible: m6A is installed by “writers”, removed by “erasers”, and recognized by “readers”. Readers are executors to regula...
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Article
Quantitative assessment of MLAA-34 expression in diagnosis and prognosis of acute monocytic leukemia
MLAA-34 is a newly identified monocytic leukemia-associated antigen. Previous data indicated that MLAA-34 might be a novel anti-apoptosis factor related closely to carcinogenesis or progression of acute monocy...