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  1. Article

    A Modeling and Simulation Framework for Adverse Events in Erlotinib-Treated Non-Small-Cell Lung Cancer Patients

    Treatment with erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor used for treating non-small-cell lung cancer (NSCLC) and other cancers, is frequently associated with adverse events (AE)...

    Ahmed Abbas Suleiman, Sebastian Frechen, Matthias Scheffler in The AAPS Journal (2015)

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    Article

    Modeling NSCLC Progression: Recent Advances and Opportunities Available

    Non-small cell lung cancer (NSCLC) is one of the leading causes of death around the world with an estimated 5-year relative survival rate of 16% at diagnosis. Development of drugs treating NSCLC is not easy, a...

    Ahmed Abbas Suleiman, Lucia Nogova, Uwe Fuhr in The AAPS Journal (2013)