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    Article

    Revitalizing antibiotic discovery and development through in vitro modelling of in-patient conditions

    In vitro models mimicking in-patient conditions have the potential to yield exciting opportunities for antibiotic research and revitalize future antibiotic discovery and development.

    Julie Sollier, Marek Basler, Petr Broz, Petra S. Dittrich… in Nature Microbiology (2024)

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    Article

    A rationally designed oral vaccine induces immunoglobulin A in the murine gut that directs the evolution of attenuated Salmonella variants

    The ability of gut bacterial pathogens to escape immunity by antigenic variation—particularly via changes to surface-exposed antigens—is a major barrier to immune clearance1. However, not all variants are equally...

    Médéric Diard, Erik Bakkeren, Verena Lentsch, Andrea Rocker… in Nature Microbiology (2021)