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Open AccessNew insights into mammalian sex chromosome structure and evolution using high-quality sequences from bovine X and Y chromosomes
Mammalian X chromosomes are mainly euchromatic with a similar size and structure among species whereas Y chromosomes are smaller, have undergone substantial evolutionary changes and accumulated male specific g...
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Article
Open AccessAutomated ensemble assembly and validation of microbial genomes
The continued democratization of DNA sequencing has sparked a new wave of development of genome assembly and assembly validation methods. As individual research labs, rather than centralized centers, begin to ...
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Article
Open AccessInteractive metagenomic visualization in a Web browser
A critical output of metagenomic studies is the estimation of abundances of taxonomical or functional groups. The inherent uncertainty in assignments to these groups makes it important to consider both their h...
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Open AccessGenomic comparison of multi-drug resistant invasive and colonizing Acinetobacter baumannii isolated from diverse human body sites reveals genomic plasticity
Acinetobacter baumannii has recently emerged as a significant global pathogen, with a surprisingly rapid acquisition of antibiotic resistance and spread within hospitals and health care institutions. This study e...
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Open AccessProbing the pan-genome of Listeria monocytogenes: new insights into intraspecific niche expansion and genomic diversification
Bacterial pathogens often show significant intraspecific variations in ecological fitness, host preference and pathogenic potential to cause infectious disease. The species of Listeria monocytogenes, a facultativ...
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Open AccessEfficient oligonucleotide probe selection for pan-genomic tiling arrays
Array comparative genomic hybridization is a fast and cost-effective method for detecting, genoty**, and comparing the genomic sequence of unknown bacterial isolates. This method, as with all microarray appl...
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Open AccessErratum to: Genome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99A
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Open AccessGenome sequence and rapid evolution of the rice pathogen Xanthomonas oryzae pv. oryzae PXO99A
Xanthomonas oryzae pv. oryzae causes bacterial blight of rice (Oryza sativa L.), a major disease that constrains production of this staple crop in many parts of the world. We report here on the complete genome se...