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    Synthesis and analgesic activity of 4-aroyl-1H-benzo[c]oxepin-3-ones

    A series of 4-aroyl-1H-benzo[c]oxepin-4-ones have been prepared by heating ethyl 2-aroyl-3-(2-bromophenyl)propenoates. The synthesized compounds possess higher analgesic activity than the reference drug (analgin)...

    A. A. Glukhov, N. F. Kirillov, A. A. Potapova… in Pharmaceutical Chemistry Journal (2010)