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  1. No Access

    Article

    The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34+ hematopoietic cells allows discrimination between normal/reactive and myelodysplastic syndrome precursors

    Occurrence of phenotypic abnormalities in CD34+ hematopoietic progenitor and precursor cells (HPC) and their major B-cell and nonlymphoid compartments has been frequently reported in myelodysplastic syndromes (MD...

    S Matarraz, A López, S Barrena, C Fernandez, E Jensen, J Flores, P Bárcena… in Leukemia (2008)

  2. No Access

    Article

    Genetic heterogeneity of BCR/ABL+ adult B-cell precursor acute lymphoblastic leukemia: impact on the clinical, biological and immunophenotypical disease characteristics

    Philadelphia-positive (Ph+) B-cell precursor acute lymphoblastic leukemia (BCP–ALL) is a genetically heterogeneous disease with a very poor prognosis. In this study, we analyzed the frequency of supernumerary Ph,...

    D Primo, M D Tabernero, J J Perez, A Rasillo, J M Sayagués, A B Espinosa… in Leukemia (2005)

  3. No Access

    Article

    Patterns of BCR/ABL gene rearrangements by interphase fluorescence in situ hybridization (FISH) in BCR/ABL+ leukemias: incidence and underlying genetic abnormalities

    Interphase fluorescence in situ hybridization (iFISH) is increasingly used for the identification of BCR/ABL gene rearrangements in chronic myeloid leukemia (CML) and acute lymphoblastic leukemia (ALL). In the pr...

    D Primo, M D Tabernero, A Rasillo, J M Sayagués, A B Espinosa, M C Chillón… in Leukemia (2003)

  4. No Access

    Article

    Adult precursor B-ALL with BCR/ABL gene rearrangements displays a unique immunophenotype based on the pattern of CD10, CD34, CD13 and CD38 expression

    The Philadelphia chromosome (Ph+) reflects a balanced reciprocal translocation between the long arms of chromosomes 9 and 22 [t(9;22)(q34;q11.2] involving the BCRand ABL genes. At present, detection of BCR/ABL ge...

    MD Tabernero, AM Bortoluci, I Alaejos, MC López-Berges, A Rasillo… in Leukemia (2001)