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  1. Article

    Open Access

    Targeting the transmembrane cytokine co-receptor neuropilin-1 in distal tubules improves renal injury and fibrosis

    Neuropilin-1 (NRP1), a co-receptor for various cytokines, including TGF-β, has been identified as a potential therapeutic target for fibrosis. However, its role and mechanism in renal fibrosis remains elusive....

    Yinzheng Li, Zheng Wang, Huzi Xu, Yu Hong, Mengxia Shi, Bin Hu in Nature Communications (2024)

  2. Article

    Open Access

    SCG5 and MITF may be novel markers of copper metabolism immunorelevance in Alzheimer’s disease

    The slow-develo** neurological disorder Alzheimer’s disease (AD) has no recognized etiology. A bioinformatics investigation verified copper metabolism indicators for AD development. GEO contributed AD-relate...

    **anbo Zhuang, Yitong **a, Yingli Liu, Tingting Guo, Zhangyong **a in Scientific Reports (2024)

  3. Article

    Open Access

    Electrical switching of Ising-superconducting nonreciprocity for quantum neuronal transistor

    Nonreciprocal quantum transport effect is mainly governed by the symmetry breaking of the material systems and is gaining extensive attention in condensed matter physics. Realizing electrical switching of the ...

    Junlin **ong, Jiao **e, Bin Cheng, Yudi Dai, **nyu Cui in Nature Communications (2024)

  4. Article

    Open Access

    Predictive value of triglyceride glucose index combined with neutrophil-to-lymphocyte ratio for major adverse cardiac events after PCI for acute ST-segment elevation myocardial infarction

    Acute ST-segment elevation myocardial infarction (STEMI) is a severe cardiovascular disease that poses a significant threat to the life and health of patients. This study aimed to investigate the predictive va...

    Long Wang, Yuqi Wang, Wei Wang, Zheng Wang in Scientific Reports (2024)

  5. Article

    Open Access

    A new seven-axis robotic-assisted total hip arthroplasty system improves component positioning: a prospective, randomized, multicenter study

    This study compared the radiologic and clinical outcomes of a new seven-axis robotic-assisted total hip arthroplasty (THA) and conventional THA. Hundred and four patients were randomly assigned to two groups—t...

    Run Tian, Xu Gao, Ning Kong, **nghua Li, Yiyang Li, Jian Wang in Scientific Reports (2024)

  6. Article

    Open Access

    Smart diabetic foot ulcer scoring system

    Current assessment methods for diabetic foot ulcers (DFUs) lack objectivity and consistency, posing a significant risk to diabetes patients, including the potential for amputations, highlighting the urgent nee...

    Zheng Wang, **nyu Tan, Yang Xue, Chen **ao, Kejuan Yue, Kaibin Lin in Scientific Reports (2024)

  7. Article

    Open Access

    Identification of candidate biomarkers for GBM based on WGCNA

    Glioblastoma multiforme (GBM), the most aggressive form of primary brain tumor, poses a considerable challenge in neuro-oncology. Despite advancements in therapeutic approaches, the prognosis for GBM patients ...

    Qinghui Sun, Zheng Wang, Hao **u, Na He, Mingyu Liu, Li Yin in Scientific Reports (2024)

  8. Article

    Open Access

    Flash heating process for efficient meat preservation

    Maintaining food safety and quality is critical for public health and food security. Conventional food preservation methods, such as pasteurization and dehydration, often change the overall organoleptic qualit...

    Yimin Mao, Peihua Ma, Tangyuan Li, He Liu, **npeng Zhao in Nature Communications (2024)

  9. Article

    Open Access

    Mutation characteristics and molecular evolution of ovarian metastasis from gastric cancer and potential biomarkers for paclitaxel treatment

    Ovarian metastasis is one of the major causes of treatment failure in patients with gastric cancer (GC). However, the genomic characteristics of ovarian metastasis in GC remain poorly understood. In this study...

    Pengfei Yu, Can Hu, Guangyu Ding, **aoliang Shi, **gli Xu in Nature Communications (2024)

  10. Article

    Open Access

    Functional alterations of the brain default mode network and somatosensory system in trigeminal neuralgia

    Map** the localization of the functional brain regions in trigeminal neuralgia (TN) patients is still lacking. The study aimed to explore the functional brain alterations and influencing factors in TN patien...

    Zairan Wang, Zijun Zhao, Zihan Song, Jiayi Xu, Yizheng Wang in Scientific Reports (2024)

  11. No Access

    Article

    A vision chip with complementary pathways for open-world sensing

    Image sensors face substantial challenges when dealing with dynamic, diverse and unpredictable scenes in open-world applications. However, the development of image sensors towards high speed, high resolution, ...

    Zheyu Yang, Taoyi Wang, Yihan Lin, Yuguo Chen, Hui Zeng, **g Pei, Jiazheng Wang in Nature (2024)

  12. Article

    Open Access

    Extra-articular screw placement strategy in Stoppa approach based on three-dimensional reconstruction model

    The study aimed to explore an extra-articular screw placement strategy in Stoppa approach. Radiographic data of patients who underwent pelvic computed tomography from January 2016 to June 2017 were imported in...

    Ruipeng Zhang, Shaojuan Zhang, Xuehong Zheng, Yingchao Yin in Scientific Reports (2024)

  13. Article

    Open Access

    Atomic-scale visualization of the interlayer Rydberg exciton complex in moiré heterostructures

    Excitonic systems, facilitated by optical pum**, electrostatic gating or magnetic field, sustain composite particles with fascinating physics. Although various intriguing excitonic phases have been revealed ...

    Meng Zhao, Zhongjie Wang, Lu Liu, Chunzheng Wang, Cheng-Yen Liu in Nature Communications (2024)

  14. Article

    Open Access

    A novel multidrug-resistant cell line from a Chinese patient with pancreatic ductal adenocarcinoma

    Chemotherapy resistance poses clinical challenges in pancreatic cancer treatment. Develo** cell lines resistant to chemotherapy is crucial for investigating drug resistance mechanisms and identifying alterna...

    Huan Tang, **n Miao, Cheng Yu, Changpeng Chai, Yuanhui Su, Lu Li in Scientific Reports (2024)

  15. Article

    Open Access

    Reconfigurable optoelectronic transistors for multimodal recognition

    Biological nervous system outperforms in both dynamic and static information perception due to their capability to integrate the sensing, memory and processing functions. Reconfigurable neuromorphic transistor...

    Pengzhan Li, Mingzhen Zhang, Qingli Zhou, Qinghua Zhang in Nature Communications (2024)

  16. Article

    Open Access

    Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion

    The mechanisms of bifurcation, a key step in thyroid development, are largely unknown. Here we find three zebrafish lines from a forward genetic screening with similar thyroid dysgenesis phenotypes and identif...

    Ya Fang, Jia-** Wan, Zheng Wang, Shi-Yang Song, Cao-Xu Zhang in Nature Communications (2024)

  17. Article

    Open Access

    DON6D: a decoupled one-stage network for 6D pose estimation

    The six-dimensional (6D) pose object estimation is a key task in robotic manipulation and gras** scenes. Many existing two-stage solutions with a slow inference speed require extra refinement to handle the c...

    Zheng Wang, Hangyao Tu, Yutong Qian, Yanwei Zhao in Scientific Reports (2024)

  18. Article

    Open Access

    Associations between corneal curvature and other anterior segment biometrics in young myopic adults

    To investigate the associations between corneal curvature (CC) and other anterior segment biometrics in young myopic adults. In this retrospective multi-center study, 7893 young myopic adults were included. CC...

    Li Jiang, Zi**g Du, Wei Sun, Shanqing Zhu, Lu **ong, Xuejun Fang in Scientific Reports (2024)

  19. Article

    Open Access

    Clinicopathological characteristics and prognosis in patients with monoclonal gammopathy and renal damage in central China: a multicenter retrospective cohort study

    Renal involvement is common in monoclonal gammopathy (MG); however, the same patient may have both MG and non-paraprotein-associated renal damage. Accordingly, distinguishing the cause of renal damage is neces...

    Huimin He, Zheng Wang, Jiayun Xu, Yun Liu, Yeqing Shao, Yulong Hou in Scientific Reports (2024)

  20. Article

    Open Access

    Extreme Li-Mg selectivity via precise ion size differentiation of polyamide membrane

    Achieving high selectivity of Li+ and Mg2+ is of paramount importance for effective lithium extraction from brines, and nanofiltration (NF) membrane plays a critical role in this process. The key to achieving hig...

    Quan Peng, Ruoyu Wang, Zilin Zhao, Shihong Lin, Ying Liu in Nature Communications (2024)

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