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  1. Article

    Open Access

    Resveratrol overcomes gefitinib resistance by increasing the intracellular gefitinib concentration and triggering apoptosis, autophagy and senescence in PC9/G NSCLC cells

    Gefitinib (Gef) provides clinical benefits to non-small cell lung cancer (NSCLC) patients with activating EGFR mutations. However, acquired resistance (AR) is a major obstacle to effective Gef therapy. This st...

    Yinsong Zhu, Wenjuan He, **ujuan Gao, Bin Li, Chenghan Mei, Rong Xu… in Scientific Reports (2015)

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  2. Article

    Open Access

    The middle lipin domain adopts a membrane-binding dimeric protein fold

    Phospholipid synthesis and fat storage as triglycerides are regulated by lipin phosphatidic acid phosphatases (PAPs), whose enzymatic PAP function requires association with cellular membranes. Using hydrogen d...

    Wei**g Gu, Shujuan Gao, Huan Wang, Kaelin D. Fleming… in Nature Communications (2021)

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