7 Result(s)
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Article
**ujuan Gao
Biomedicine
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Article
Open AccessExosomal circRNAs in the plasma serve as novel biomarkers for IPF diagnosis and progression prediction
Idiopathic Pulmonary Fibrosis (IPF) is a type of chronic interstitial pneumonia, often fatal, with elusive causes and a bleak prognosis. Its treatment options are limited and largely ineffective. Early detecti...
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Article
Altered cerebral blood flow in older adults with Alzheimer’s disease: a systematic review
The prevalence of Alzheimer’s disease is projected to reach 13 million in the U.S. by 2050. Although major efforts have been made to avoid this outcome, so far there are no treatments that can stop or reverse ...
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Article
Open AccessEstrogen receptors promote NSCLC progression by modulating the membrane receptor signaling network: a systems biology perspective
Estrogen receptors (ERs) are thought to play an important role in non-small cell lung cancer (NSCLC). However, the effect of ERs in NSCLC is still controversial and needs further investigation. A new considera...
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Open AccessFOXC1 induces cancer stem cell-like properties through upregulation of beta-catenin in NSCLC
Accumulating evidence suggests that cancer stem cells (CSCs) play a critical role in tumor initiation, progression and therapy, and recent studies have indicated that Forkhead box C1 (FOXC1) is strongly associ...
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Open AccessmiR-143 and miR-145 synergistically regulate ERBB3 to suppress cell proliferation and invasion in breast cancer
ERBB3, one of the four members of the ErbB family of receptor tyrosine kinases, plays an important role in breast cancer etiology and progression. In the present study, we aimed to identify novel miRNAs that c...
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Identification of host range mutants of myxoma virus with altered oncolytic potential in human glioma cells
The authors have recently demonstrated that wild-type myxoma virus (MV) tagged with gfp (vMyxgfp) can generate a tumor-specific infection that productively infects and clears human tumor-derived xenografts whe...
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Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier
Myxoma virus, a member of the poxvirus family, causes lethal infection only in rabbits, but the mechanism underlying the strict myxoma virus species barrier is not known. Here we show that myxoma virus infecti...
