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Open AccessMultimodal evaluation of the effects of low-intensity ultrasound on cerebral blood flow after traumatic brain injury in mice
Traumatic brain injury (TBI) is one of the leading causes of death and disability worldwide, and destruction of the cerebrovascular system is a major factor in the cascade of secondary injuries caused by TBI. ...
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Article
Open AccessTypical metabolic pattern of 18F-FDG PET in Anti-NMDAR encephalitis in the acute and subacute phases and its correlation with T2 FLAIR-MRI features
Early diagnosis of Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis with non-invasive imaging modalities benefiting is crucial to guarantee prompt treatments decision-making and good prognosis for ...
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Open AccessStudy of extravisual resting-state networks in pituitary adenoma patients with vision restoration
Pituitary adenoma (PA) may compress the optic apparatus, resulting in impaired vision. Some patients can experience improved vision rapidly after surgery. During the early period after surgery, however, the ch...
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Open AccessSaccharomyces boulardii improves the behaviour and emotions of spastic cerebral palsy rats through the gut-brain axis pathway
Cerebral palsy (CP) is a kind of disability that influences motion, and children with CP also exhibit depression-like behaviour. Inflammation has been recognized as a contributor to CP and depression, and some...
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Open AccessSCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves
The SCN11A gene, encoded Nav1.9 TTX resistant sodium channels, is a main effector in peripheral inflammation related pain in nociceptive neurons. The role of SCN11A gene in the auditory system has not been well c...
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Open AccessCorrection to: The role of C-afferents in mediating neurogenic vasodilatation in plantar skin after acute sciatic nerve injury in rats
An amendment to this paper has been published and can be accessed via the original article.
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Open AccessThe role of C-afferents in mediating neurogenic vasodilatation in plantar skin after acute sciatic nerve injury in rats
Vasomotor regulation of dermal blood vessels, which are critical in the function of the skin in thermoregulatory control, involves both neural and non-neural mechanisms. Whereas the role of sympathetic nerves ...
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Open AccessThe modulation effect of non-invasive brain stimulation on cognitive function in patients with mild cognitive impairment: a systematic review and meta-analysis of randomized controlled trials
To prevent and control dementia, many scholars have focused on the transition stage between normal ageing and dementia, mild cognitive impairment (MCI) which is a key interventional target for dementia. Studie...
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Open Access26th Annual Computational Neuroscience Meeting (CNS*2017): Part 2
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Open AccessRoles of NMDA and dopamine in food-foraging decision-making strategies of rats in the social setting
In highly complex social settings, an animal’s motivational drive to pursue an object depends not only on the intrinsic properties of the object, but also on whether the decision-making animal perceives an ob...
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Open AccessA spiking neuron network model for the delayed motion direction discrimination task
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Open AccessLithium protects dopaminergic cells from rotenone toxicity via autophagy enhancement
Previous studies have indicated that enhancement of autophagy lysosome pathway may be beneficial for Parkinson’s disease (PD), in which aberrant accumulation of aggregated/misfolded proteins and mitochondrial ...
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Open AccessMethamphetamine induces alterations in the long non-coding RNAs expression profile in the nucleus accumbens of the mouse
Repeated exposure to addictive drugs elicits long-lasting cellular and molecular changes. It has been reported that the aberrant expression of long non-coding RNAs (lncRNAs) is involved in cocaine and heroin a...
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Open AccessDifferential roles of hippocampal glutamatergic receptors in neuropathic anxiety-like behavior after partial sciatic nerve ligation in rats
Neuropathic pain evoked by nerve injury is frequently accompanied by deterioration of emotional behaviors, but the underlying signaling mechanisms remain elusive. Glutamate (Glu) is the major mediator of excit...
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Open AccessNoise alters guinea pig’s blood-labyrinth barrier ultrastructure and permeability along with a decrease of cochlear Claudin-5 and Occludin
Noise exposure (NE) is a severe modern health hazard that induces hearing impairment. However, the noise-induced ultrastructural changes of blood-labyrinth barrier (BLB) and the potential involvements of tight...
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Open AccessMAPT rs242562 and GSK3B rs334558 are associated with Parkinson’s Disease in central China
Microtubule-associated protein tau (MAPT) is a neuronal protein involved in the pathogenesis of several neurodegenerative diseases including Parkinson’s Disease (PD). Glycogen synthase kinase 3 beta (GSK3B) ca...
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Open AccessDNA methylation profiling in the thalamus and hippocampus of postnatal malnourished mice, including effects related to long-term potentiation
DNA methylation has been viewed as the most highly characterized epigenetic mark for genome regulation and development. Postnatal brains appear to exhibit stimulus-induced methylation changes because of factor...
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Open AccessSpatio-temporal expression of a novel neuron-derived neurotrophic factor (NDNF) in mouse brains during development
Neuron-derived neurotrophic factor (NDNF) is evolutionarily well conserved, being present in invertebrate animals such as the nematode, Caenorhabditis elegans, as well as in the fruit fly, Drosophila melanogaster
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Open AccessProteomic characterization of an isolated fraction of synthetic proteasome inhibitor (PSI)-induced inclusions in PC12 cells might offer clues to aggresomes as a cellular defensive response against proteasome inhibition by PSI
Cooperation of constituents of the ubiquitin proteasome system (UPS) with chaperone proteins in degrading proteins mediate a wide range of cellular processes, such as synaptic function and neurotransmission, g...
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Open AccessEffects of dietary Na+ deprivation on epithelial Na+ channel (ENaC), BDNF, and TrkB mRNA expression in the rat tongue
In rodents, dietary Na+ deprivation reduces gustatory responses of primary taste fibers and central taste neurons to lingual Na+ stimulation. However, in the rat taste bud cells Na+ deprivation increases the numb...