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Article
Open AccessMitochondrial Adaptation in Skeletal Muscle: Impact of Obesity, Caloric Restriction, and Dietary Compounds
The global obesity epidemic has become a major public health concern, necessitating comprehensive research into its adverse effects on various tissues within the human body. Among these tissues, skeletal muscl...
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Article
Open AccessDesigning strategies to support Implementation of iNtensive Therapy for Early Reach through PLAY (INTERPLAY) for young children with cerebral palsy: a study protocol
Intensive manual therapy is important for improving lifelong upper limb motor outcomes for infants and toddlers with cerebral palsy. This play-based therapy is delivered by caregivers who are coached by occupa...
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Article
Open AccessLactobacillus alleviates intestinal epithelial barrier function through GPR43-mediated M2 macrophage polarization
Lactobacillus species have excellent abilities to reduce intestinal inflammation and enhance gut barrier function. This study elucidated the potential mechanisms through which Lactobacillus mitigates lipopolysacc...
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Article
Open AccessComparison of smokers’ mortality with non-smokers following out-of-hospital cardiac arrests: a systematic review and meta-analysis
Although some studies have linked smoking to mortality after out-of-hospital cardiac arrests (OHCAs), data regarding smoking and mortality after OHCAs have not yet been discussed in a meta-analysis. Thus, this...
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Article
Open AccessEffects of whole grains on glycemic control: a systematic review and dose-response meta-analysis of prospective cohort studies and randomized controlled trials
Whole grains have recently been promoted as beneficial to diabetes prevention. However, the evidence for the glycemic benefits of whole grains seems to conflict between the cohort studies and randomized contro...
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Article
Association of socioeconomic status with cardiovascular disease and cardiovascular risk factors: a systematic review and meta-analysis
Cardiovascular disease (CVD) remains one of the leading causes of mortality worldwide, and several studies have indicated the association between socioeconomic status (SES) with CVD and cardiovascular risk fac...
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Article
Open AccessCodon usage and evolutionary dynamics of genetic diversity of novel imported porcine reproductive and respiratory syndrome virus in China
Porcine reproductive and respiratory syndrome (PRRS) is a problem that has significant economic impact on the global pig industry. In recent years, there has been an increased importation of pork into China, c...
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Article
Open AccessEstablishing performance standards for child development: learnings from the ECDI2030
Standards of early childhood development (ECD) are needed to determine whether children living in different contexts are developmentally on track. The Early Childhood Development Index 2030 (ECDI2030) is a pop...
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Article
Open AccessDifferent types of screen time, physical activity, and incident dementia, Parkinson’s disease, depression and multimorbidity status
Several previous studies have shown that excessive screen time is associated with an increased prevalence of dementia, Parkinson’s disease (PD), and depression. However, the results have been inconsistent. Thi...
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Article
Open AccessTransmembrane protein 117 knockdown protects against angiotensin-II-induced cardiac hypertrophy
Mitochondrial dysfunction plays a critical role in the pathogenesis of pathological cardiac hypertrophy. Transmembrane protein 117 modulate mitochondrial membrane potential that may be involved in the regulati...
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Article
Control status of ambulatory blood pressure and its relationship with arterial stiffness in the China nationwide registry of treated hypertensive patients: the REACTION-ABP study
The control rate of ambulatory blood pressure (BP) is unclear in Chinese hypertensive patients, and whether it would be associated with the ambulatory arterial stiffness indices is also unknown. From June 2018...
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Article
Open AccessAccelerometer-measured sedentary behavior and risk of functional disability in older Japanese adults: a 9-year prospective cohort study
The associations of sedentary time and patterns with functional disability among older adults remain unclear, and few studies have accounted for the co-dependency of sedentary behavior and physical activities ...
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Article
Open AccessRelationship between dietary pattern and depressive symptoms: an international multicohort study
Several previous studies have shown that dietary patterns are associated with the incidence of depressive symptoms. However, the results have been inconsistent. This study aimed to prospectively investigate th...
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Article
Open AccessRelationship between socioeconomic status and cognitive ability among Chinese older adults: the moderating role of social support
Understanding the causes and pathways of cognitive decline among older populations is of great importance in China. This study aims to examine whether the discrepancy in socioeconomic status (SES) makes a diff...
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Article
Open AccessRelationship between 25-hydroxyvitamin D and IGF1: a cross-sectional study of the Third National Health and Nutrition Examination Survey participants
25-Hydroxyvitamin D (25OHD) and insulin-like growth factor 1 (IGF1) are crucial for bone health. Some studies have shown that they interact, whereas others have indicated no association. However, it remains in...
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Article
Open AccessAssociation between physical activity and cancer risk among Chinese adults: a 10-year prospective study
In China, the quantity of physical activity differs from that in Western countries. Substantial uncertainty remains about the relevance of physical activity for cancer subtypes among Chinese adults.
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Article
C/EBPZ modulates the differentiation and proliferation of preadipocytes
This study investigated the functions of CCAAT/enhancer-binding protein zeta (C/EBPZ; Gene ID: 10153) in adipose tissue.
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Article
The clinical data from 19 critically ill patients with coronavirus disease 2019: a single-centered, retrospective, observational study
The objectives of this study were to analyze the clinical features of coronavirus disease 2019 (COVID-19) and evaluate the diagnosis and treatment.
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Article
Open AccessDevelopment of an accurate lateral flow immunoassay for PEDV detection in swine fecal samples with a filter pad design
Porcine epidemic diarrhea virus (PEDV), as the main causative pathogen of viral diarrhea in pigs, has been reported to result in high morbidity and mortality in neonatal piglets and cause significant economic ...
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Article
Open AccessAssociations between screen time, physical activity, and depressive symptoms during the 2019 coronavirus disease (COVID-19) outbreak among Chinese college students
The 2019 novel coronavirus disease (COVID-19) emerges in China, which spreads rapidly and becomes a public health emergency of international concern. Chinese government has promptly taken quarantine measures t...