4 Result(s)
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Article
Open AccessGenome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging
Biological aging estimators derived from DNA methylation data are heritable and correlate with morbidity and mortality. Consequently, identification of genetic and environmental contributors to the variation i...
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Article
Open AccessIn silico drug repositioning using deep learning and comprehensive similarity measures
Drug repositioning, meanings finding new uses for existing drugs, which can accelerate the processing of new drugs research and development. Various computational methods have been presented to predict novel d...
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Article
Open AccessGenomes of the rice pest brown planthopper and its endosymbionts reveal complex complementary contributions for host adaptation
The brown planthopper, Nilaparvata lugens, the most destructive pest of rice, is a typical monophagous herbivore that feeds exclusively on rice sap, which migrates over long distances. Outbreaks of it have re-occ...
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Article
Genome-wide Comparisons of Gene Expression for Yield Heterosis in Maize
Although heterosis is widely used in conventional plant breeding, its genetic mechanism has not been well understood at the molecular level. In this study, we identified a highly heterotic hybrid (C8605-2 × W1...
