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Article
Open AccessLong-term survivals of immune checkpoint inhibitors as neoadjuvant and adjuvant therapy in dMMR/MSI-H colorectal and gastric cancers
The long-term survival benefit of immune checkpoint inhibitors (ICIs) in neoadjuvant and adjuvant settings is unclear for colorectal cancers (CRC) and gastric cancers (GC) with deficiency of mismatch repair (d...
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Article
High-Temperature Corrosion Characterization of Ni-Al Laser Cladding: The Effect of Al Content and Fe
To further enhance the high-temperature corrosion resistance of boiler tubes for improved power generation efficiency of biomass and waste-to-energy plants, Ni-Al cladding layers with Al contents of 2, 4, 6 an...
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Article
Fine-map** and validation of the major quantitative trait locus QFlANG-4B for flag leaf angle in wheat
This study precisely mapped and validated a quantitative trait locus (QTL) located on chromosome 4B for flag leaf angle in wheat.
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Article
Players behind the scenes: common ownership in the hospital industry
Publicly traded firms being held by common owners may affect product prices set by these firms. Common ownership usually refers to a scenario when a few competing firms from the same industry and competing fir...
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Article
Open AccessSpecific lineage transition of tumor-associated macrophages elicits immune evasion of ascitic tumor cells in gastric cancer with peritoneal metastasis
Gastric cancer with peritoneal metastasis (PM-GC), recognized as one of the deadliest cancers. However, whether and how the tumor cell-extrinsic tumor microenvironment (TME) is involved in the therapeutic fail...
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Open AccessAnalyzing the changing trend of corneal biomechanical properties under different influencing factors in T2DM patients
To analyze the changing trend of CH and CRF values under different influencing factors in T2DM patients. A total of 650 patients with T2DM were included. We discovered that the course of T2DM, smoking history,...
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Article
Open AccessInfluential upregulation of KCNE4: Propelling cancer associated fibroblasts-driven colorectal cancer progression
Colorectal cancer (CRC) is a malignancy of remarkable heterogeneity and heightened morbidity. Cancer associated fibroblasts (CAFs) are abundant in CRC tissues and are essential for CRC growth. Here, we aimed t...
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Article
A creep damage model for yellow sandstone under the action of wetting-drying cycles
Regarding the issue of creep characteristics of the rock mass following excavation or excavation with graded loading and unloading under external forces. This study performs uniaxial compression and step loadi...
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Open AccessPore structure characterization of sandstone under different water invasion cycles using micro-CT
The meso-structural changes of rocks during repeated cycles of water invasion are the fundamental cause of macroscopic physical property damage. In this paper, based on the computed tomography scan images of r...
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Article
Comparative study on the performance of different slope protective measures under rainfall conditions: the case study of Qingyang City, China
This study addresses the challenge of deformation and failure on loess slopes, predominantly triggered by rainfall, by evaluating the efficacy of various slope protective measures. Recognizing the escalating p...
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Article
Effect of Long-Term Thermal Aging at 680 °C on Microstructure and Mechanical Properties of P92 Steel
The stability of microstructure and performance after long-term service are crucial for the engineering application of ASME SA335-P92 steel. In this present work, a series of isothermal aging tests for P92 ste...
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Open AccessClaudin-18.2 mediated interaction of gastric Cancer cells and Cancer-associated fibroblasts drives tumor progression
Claudin-18.2 (CLDN18.2) has emerged as an alluring therapeutic target against gastrointestinal tumors in recent years. However, a thorough understanding of its regulatory mechanism in gastric cancer remains el...
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Article
Origin of the DUPAL anomaly in the Tethyan mantle domain and its geodynamic significance
Mantle heterogeneity has revealed systematic differences in Pb isotopic compositions between the Indian Ocean-South Atlantic mantle in the Southern Hemisphere and the Pacific Ocean-North Atlantic mantle in the...
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Open AccessResearch on permanent magnet synchronous motor algorithm based on linear nonlinear switching self-disturbance rejection control
This paper presents a linear-nonlinear switching control strategy, called Switching Active Disturbance Rejection Control (SADRC), to enhance the disturbance rejection capability of the speed controller in a se...
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Adsorption of Methylene Blue from High-Salt Wastewater by Construction and Demolition Waste-Based Chabazite
In this study, construction and demolition waste (CDW) were selected as raw material to prepare chabazite by alkali fusion hydrothermal method. The obtained chabazite was utilized in adsorbing methylene blue f...
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Article
A self-power photodetector based on controlled growth of single crystal MAPbBr3/WO3 heterojunction
Compared with polycrystalline films, perovskite single crystal is considered as a promising photoelectric material due to its unique advantages in quantum efficiency and carrier diffusion length. In this work,...
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Article
Open AccessCharacteristics, prognostic determinants of monocytes, macrophages and T cells in acute coronary syndrome: protocol for a multicenter, prospective cohort study
Acute coronary syndrome(ACS) is the leading cause of mortality and disability worldwide. Immune response has been confirmed to play a vital role in the occurrence and development of ACS. The objective of this ...
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Article
Efficient adsorption of tetracycline hydrochloride by Willow Catkins based biochar: Performance, governing factors and mechanisms
This work prepared a novel biochar from willow catkins (WC) by a two-step pyrolysis and KOH activate to adsorb tetracycline hydrochloride (TCH) in water. The effects of pyrolysis temperature and activator amou...
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Article
Atomic Bose–Einstein condensate in twisted-bilayer optical lattices
Observation of strong correlations and superconductivity in twisted-bilayer graphene1–4 has stimulated tremendous interest in fundamental and applied physics5–8. In this system, the superposition of two twisted h...
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Article
Open AccessDesign and performance analysis of 3D-printed stiffness gradient femoral scaffold
Studies on 3D-printed porous bone scaffolds mostly focus on materials or structural parameters, while the repair of large femoral defects needs to select appropriate structural parameters according to the need...
