124 Result(s)
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Article
**guang Gu
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The neuronal and synaptic dynamics underlying post-inhibitory rebound burst related to major depressive disorder in the lateral habenula neuron model
A burst behavior observed in the lateral habenula (LHb) neuron related to major depressive disorder has attracted much attention. The burst is induced from silence by the excitatory N-methyl-D-aspartate (NMDA) sy...
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Dynamics of interaction between IH and IKLT currents to mediate double resonances of medial superior olive neurons related to sound localization
Neurons in the medial superior olive (MSO) exhibit high frequency responses such as subthreshold resonance, which is helpful to sensitively detect a small difference in the arrival time of sounds between two e...
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The influence of hyperpolarization-activated cation current on conduction delay and failure of action potentials along axon related to abnormal functions
Conduction delay and failure behaviors of action potentials with a high frequency along nerve fiber are related to the abnormal functions. For instance, upregulation of a hyperpolarization-activated cation cur...
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Rare earth elements in sediments of the Pearl River Estuary, China: distribution, influencing factors, and multi-index assessment
The main objectives of this study were to investigate the distribution characteristics and evaluate the potential ecological hazard associated with rare earth elements (REEs) within the Pearl River Estuary (PR...
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Research and prospect of novel WC-HEA cemented carbide
With the rapid development of industrial manufacturing, traditional WC–Co cemented carbides have exposed more and more problems. Therefore, the preparation of ultrafine/nanocrystalline-grained cemented carbide...
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Identifying bifurcations underlying a neuronal bursting of mixed-mode oscillations with two slow variables in inner hair cell
Neuronal bursting patterns are nonlinear behaviors related to various brain functions and diseases. Bursting modulated by two slow variables manifest more complex dynamics than that with one slow variable, due...
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Open AccessDNA damage response and repair gene mutations are associated with tumor mutational burden and outcomes to platinum-based chemotherapy/immunotherapy in advanced NSCLC patients
DNA damage response and repair (DDR) genes are crucial for maintaining the integrity of the genome. This study aims to explore the correlation of DDR gene mutations with TMB, clinical characteristics, and outc...
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The anthropogenic effects on organic matter in sediment core based on Bayesian mixing model: a case study of Daya Bay
Sediment is an important carrier of evidence about environmental evolution which receives huge volumes of organic material originated from both anthropogenic and natural sources. In this study, based on sedime...
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Influence of inhibitory autapses on synchronization of inhibitory network gamma oscillations
A recent experimental study showed that inhibitory autapses favor firing synchronization of parvalbumin interneurons in the neocortex during gamma oscillations. In the present paper, to provide a comprehensive...
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Nonlinear mechanism for the enhanced bursting activities induced by fast inhibitory autapse and reduced activities by fast excitatory autapse
The paradoxical phenomena that excitatory modulation does not enhance but reduces or inhibitory modulation not suppresses but promotes neural firing activities have attracted increasing attention. In the prese...
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Ecotoxicological risk of antibiotics and their mixtures to aquatic biota with the DGT technique in sediments
Antibiotics are emerging contaminants and widely used in human healthcare, livestock, and aquaculture. The toxicity posed by antibiotics and their mixtures in sediments depends on their bioavailability. Now, t...
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Nonlinear mechanisms for opposite responses of bursting activities induced by inhibitory autapse with fast and slow time scale
Fast and slow inhibitory synapses, respectively, induce anti- and in-phase synchronizations, showing different roles of synapse with different time scales. In the present paper, the opposite roles of inhibitor...
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Open AccessOpsin 3 mediates UVA-induced keratinocyte supranuclear melanin cap formation
Solar ultraviolet (UV) radiation-induced DNA damage is a major risk factor for skin cancer development. UV-induced redistribution of melanin near keratinocyte nuclei leads to the formation of a supranuclear ca...
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A Fourth-Order Unstructured NURBS-Enhanced Finite Volume WENO Scheme for Steady Euler Equations in Curved Geometries
In Li and Ren (Int. J. Numer. Methods Fluids 70: 742–763, 2012), a high-order k-exact WENO finite volume scheme based on secondary reconstructions was proposed to solve the two-dimensional time-dependent Euler eq...
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Metal Biological Enrichment Capacities, Distribution Patterns, and Health Risk Implications in Sea Bass (Lateolabrax japonicus)
Seabass (Lateolabrax japonicus) is a major aquacultured fish species worldwide. The bioconcentration, bioaccumulation, and biomagnification of metals in water, sediments, and commercial feed were investigated in
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Bifurcations underlying sigh and eupnea rhythmic transition in a pre-Bötzinger complex model
Neuronal networks control motor output through multi-rhythmic electrical activities with different frequencies and amplitudes of different neurons. For example, the pre-Bötzinger complex related to respiratory...
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Open AccessMental health in children with living donor liver transplantation: a propensity score-matched analysis
This study explored mental health of pediatric patients with living donor liver transplantation.
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Complex dynamics of hair bundle of auditory nervous system (II): forced oscillations related to two cases of steady state
The forced oscillations of hair bundle of inner hair cells of auditory nervous system evoked by external force from steady state are related to the fast adaption of hair cells, which are very important for aud...
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Complex dynamics of hair bundle of auditory nervous system (I): spontaneous oscillations and two cases of steady states
The hair bundles of inner hair cells in the auditory nervous exhibit spontaneous oscillations, which is the prerequisite for an important auditory function to enhance the sensitivity of inner ear to weak sound...
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Open AccessThe genomic and transcriptional landscape of primary central nervous system lymphoma
Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell lymphomas (DLBCLs) confined to the central nervous system (CNS). Molecular drivers of PCNSL have not been fully elucidate...
