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    Targeting acute hypoxic cancer cells by doxorubicin-immunoliposomes directed by monoclonal antibodies specific to RON receptor tyrosine kinase

    Hypoxia contributes to acquired drug resistance in various cancer cells. The underlying mechanism is cellular insensitivity regulated by hypoxia-inducible factors (HIF), which impairs drug uptake, transport, a...

    Sunny Guin, Qi Ma, Snehal Padhye, Yong-Qing Zhou… in Cancer Chemotherapy and Pharmacology (2011)