27 Result(s)
within
English
Science, multidisciplinary
**g-Yao Jiang
Article
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Article
Open AccessThe anti-fibrotic effects of mesenchymal stem cells on irradiated lungs via stimulating endogenous secretion of HGF and PGE2
Radiation-induced pulmonary fibrosis is a common disease and has a poor prognosis owing to the progressive breakdown of gas exchange regions in the lung. Recently, a novel strategy of administering mesenchymal...
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Open AccessHigh-throughput sequencing of small RNAs and anatomical characteristics associated with leaf development in celery
MicroRNAs (miRNAs) exhibit diverse and important roles in plant growth, development and stress responses and regulate gene expression at the post-transcriptional level. Knowledge about the diversity of miRNAs ...
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Open AccessGenetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
The genome sequences of 175 Ebola virus from five districts in Sierra Leone, collected during September–November 2014, show that the rate of virus evolution seems to be similar to that observed during previous...
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Erratum: Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone
Nature 524, 93–96 (2015); doi:10.1038/nature14490 This Letter should have contained an associated Creative Commons statement in the Author Information section. In addition, the Fig. 3c legend should have state...
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Open AccessLow c-Met expression levels are prognostic for and predict the benefits of temozolomide chemotherapy in malignant gliomas
Aberrant c-Met has been implicated in the development of many cancers. The objective of this study was to identify an unfavorable prognostic marker that might guide decisions regarding clinical treatment strat...
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Open AccessSmad3 promotes cancer progression by inhibiting E4BP4-mediated NK cell development
TGF-β is known to influence tumour progression. Here we report an additional role of Smad3 in the tumour microenvironment regulating cancer progression. Deletion or inhibition of Smad3 in the tumour microenvir...
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Open AccessHigh photon-to-heat conversion efficiency in the wavelength region of 250–1200 nm based on a thermoelectric Bi2Te3 film structure
In this work, 4-layered SiO2/Bi2Te3/SiO2/Cu film structures were designed and fabricated and the optical properties investigated in the wavelength region of 250–1200 nm for their promising applications for direct...
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Open AccessLipoprotein-biomimetic nanostructure enables efficient targeting delivery of siRNA to Ras-activated glioblastoma cells via macropinocytosis
Hyperactivated Ras regulates many oncogenic pathways in several malignant human cancers including glioblastoma and it is an attractive target for cancer therapies. Ras activation in cancer cells drives protein in...
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Open AccessTranscriptome analysis explores genes related to shikonin biosynthesis in Lithospermeae plants and provides insights into Boraginales’ evolutionary history
Shikonin and its derivatives extracted from Lithospermeae plants’ red roots have current applications in food and pharmaceutical industries. Previous studies have cloned some genes related to shikonin biosynth...
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Open AccessSpleen contributes to restraint stress induced changes in blood leukocytes distribution
Psychological stress has great impacts on the immune system, particularly the leukocytes distribution. Although the impacts of acute stress on blood leukocytes distribution are well studied, however, it remain...
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Open AccessNovel halos in light kaonic nuclei as an indicator of nuclear equation of state at supra-normal densities
The sensitive correlations between the low-density halo structure and the high-density properties of the nuclear equation of state (EOS) are constructed in light kaonic nuclei with the relativistic mean-field ...
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Open AccessDevelopment of a chimeric Zika vaccine using a licensed live-attenuated flavivirus vaccine as backbone
The global spread of Zika virus (ZIKV) and its unexpected association with congenital defects necessitates the rapid development of a safe and effective vaccine. Here we report the development and characteriza...
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Open AccessA High-Performance Spectrometer with Two Spectral Channels Sharing the Same BSI-CMOS Detector
Optical spectrometers play an important role in modern scientific research. In this work, we present a two-channel spectrometer with a pixel resolution of better than 0.1 nm/pixel in the wavelength range of 20...
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Open AccessDietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)
Grass carp (223.85–757.33 g) were fed diets supplemented with magnesium (73.54–1054.53 mg/kg) for 60 days to explore the impacts of magnesium deficiency on the growth and intestinal structural integrity of the...
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Open AccessPES1 promotes the occurrence and development of papillary thyroid cancer by upregulating the ERα/ERβ protein ratio
PES1, a BRCT domain-containing protein, has been shown to play a role in modulating the balance and ratio between ERα and ERβ protein, which is involved in the occurrence and development of breast and ovarian ...
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Open AccessMERTK mediated novel site Akt phosphorylation alleviates SAV1 suppression
Akt plays indispensable roles in cell proliferation, survival and metabolism. Mechanisms underlying posttranslational modification-mediated Akt activation have been extensively studied yet the Akt interactome ...
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Open AccessUltrahigh-resolution spectrometer based on 19 integrated gratings
Optical spectrometers play a key role in acquiring rich photonic information in both scientific research and a wide variety of applications. In this work, we present a new spectrometer with an ultrahigh resolu...
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Open AccessStrong optical absorption of a metallic film to induce a lensing effect in the visible region
In this work, the two-dimensional profile of the light transmission through a prism-like metallic film sample of Au was measured at a wavelength of 632.8 nm in the visible intraband transition region to verify...
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Open AccessMagnon-tuning non-volatile magnetic dynamics in a CoZr/PMN-PT structure
Magnon-tuning non-volatile magnetic dynamics is investigated in a CoZr/PMN-PT structure by measuring ferromagnetic resonance at room temperature. The electric-field control of ferromagnetic resonance shows loop-l...
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Open AccessPrecise diagnosis of three top cancers using dbGaP data
The challenge of decoding information about complex diseases hidden in huge number of single nucleotide polymorphism (SNP) genotypes is undertaken based on five dbGaP studies. Current genome-wide association s...
