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  1. No Access

    Article

    Increased gene expression of β-1,4-galactosyltransferase I in rat injured sciatic nerve

    During neurite outgrowth on basal lamina, cell-surface β-1,4-galactosyltransferase I (β-1,4-GalT-I) functions as one of the receptors of laminin by binding to N-linked oligosaccharides on the laminin E8 domain. I...

    Aiguo Shen, Dan Zhu, Fei Ding, Min Zhu, **aosong Gu in Journal of Molecular Neuroscience (2003)

  2. No Access

    Article

    EST-based identification of genes expressed in brain and spinal cord of Gekko japonicus, a species demonstrating intrinsic capacity of spinal cord regeneration

    In the present study, a brain and spinal cord cDNA library of Gekko japonicus was constructed, and 2349 unique expressed sequence tags (ESTs), composed of 494 clusters and 1855 singletons, were determined from 41...

    Yan Yiu, Fei Ding, Mei Liu, Maorong Jiang, Hui Yang in Journal of Molecular Neuroscience (2006)

  3. No Access

    Article

    Tpc1808 increases expression of NF-H in PC12 cells

    Tpc1808 is a candidate chemotropic factor induced by nerve injury, and we report here the role of rat Tpc1808 in the expression of high-molecular-weight neurofilament (NF-H) in PC12 cells...

    Mei Liu, **aosong Gu, Qi Zhang, Yan Liu, Sheyu Lin in Journal of Molecular Neuroscience (2006)

  4. No Access

    Article

    Neuroprotective Effects of Salidroside in the PC12 Cell Model Exposed to Hypoglycemia and Serum Limitation

    The hypoglycemia and serum limitation-induced cell death in cultured PC12 cells represents a useful in vitro model for the study of brain ischemia and neurodegenerative disorders. Salidroside is a phenylpropan...

    Shu Yu, Mei Liu, **aosong Gu, Fei Ding in Cellular and Molecular Neurobiology (2008)

  5. No Access

    Article

    The Molecular Cloning of Platelet-Derived Growth Factor-C (PDGF-C) Gene of Gekko japonicus and Its Expression Change in the Spinal Cord After Tail Amputation

    The platelet-derived growth factor-C (PDGF-C) gene of Gekko japonicus was obtained from a brain and spinal cord cDNA library. The results of Northern blot showed that transcript of PDGF-C gene of gecko is 2.8 kb ...

    Yan Liu, Zheng Fan, Youlang Zhou, Mei Liu, Fei Ding in Cellular and Molecular Neurobiology (2009)

  6. No Access

    Article

    Effects of Bone Marrow Stromal Cell-conditioned Medium on Primary Cultures of Peripheral Nerve Tissues and Cells

    Implantation of bone marrow stromal cells (MSCs) produces an improved functional outcome of peripheral nerve repair. In this study, rat dorsal root ganglion (DRG) explants, rat DRG neurons, and rat Schwann cel...

    Jiajiong Yang, Hong Wu, Nan Hu, **aosong Gu, Fei Ding in Neurochemical Research (2009)

  7. No Access

    Article

    Neurotrophic Actions of Bone Marrow Stromal Cells on Primary Culture of Dorsal Root Ganglion Tissues and Neurons

    Application of adult bone marrow stromal cells (BMSCs) provides therapeutic benefits to the treatment of neurological insults. The aim of this study was to explore the potential of nonhematopoietic BMSCs to pr...

    Yun Gu, Jie Wang, Fei Ding, Nan Hu, Yaxian Wang in Journal of Molecular Neuroscience (2010)

  8. No Access

    Article

    Cyclic AMP-Dependent Protein Kinase Enhances SC35-Promoted Tau Exon 10 Inclusion

    Alternative splicing of tau exon 10 generates tau with three or four microtubule-binding repeats (3R-tau or 4R-tau). The ratio of 3R-tau to 4R-tau is approximately 1:1 in the adult normal human brain. Disturba...

    Caoyi Chen, Nana **, Wei Qian, Wen Liu, **angling Tan, Fei Ding in Molecular Neurobiology (2014)

  9. No Access

    Article

    Basic Fibroblast Growth Factor (bFGF) Facilitates Differentiation of Adult Dorsal Root Ganglia-Derived Neural Stem Cells Toward Schwann Cells by Binding to FGFR-1 Through MAPK/ERK Activation

    Considerable research has been devoted to unraveling the regulation of neural stem cell (NSC) differentiation. The responses of NSCs to various differentiation-inducing stimuli, however, are still difficult to...

    Yun Gu, Chenbin Xue, Jianbin Zhu, Hualin Sun, Fei Ding in Journal of Molecular Neuroscience (2014)

  10. No Access

    Article

    The Regenerating Spinal Cord of Gecko Maintains Unaltered Expression of β-Catenin Following Tail Amputation

    The Wingless/Integrated (Wnt) signaling pathway plays important roles in central nervous system (CNS) development and regeneration, and β-catenin, the central component, has been considered in association with...

    Honghua Song, Lili Man, Yingjie Wang, Xue Bai in Journal of Molecular Neuroscience (2015)

  11. No Access

    Article

    Chitosan Degradation Products Promote Nerve Regeneration by Stimulating Schwann Cell Proliferation via miR-27a/FOXO1 Axis

    Natural polysaccharides are biomaterials widely used for constructing scaffolds in tissue engineering. While natural polysaccharides have been shown to robustly promote tissue regeneration, the underlying mole...

    Yongjun Wang, Yahong Zhao, Cheng Sun, Wen Hu, **g Zhao in Molecular Neurobiology (2016)

  12. No Access

    Article

    Hypoxia-Induced Upregulation of miR-132 Promotes Schwann Cell Migration After Sciatic Nerve Injury by Targeting PRKAG3

    Following peripheral nerve injury, hypoxia is formed as a result of defects in blood supply at the injury site. Despite accumulating evidence on the effects of microRNAs (miRNAs) on phenotype modulation of Sch...

    Chun Yao, **angxiang Shi, Zhanhu Zhang, Songlin Zhou in Molecular Neurobiology (2016)

  13. No Access

    Article

    MiR-340 Regulates Fibrinolysis and Axon Regrowth Following Sciatic Nerve Injury

    After peripheral nerve injury, the degenerative debris and inflammatory alterations at the injury site may block the elongation of regenerating axons to reach target organs. Tissue plasminogen activator (tPA),...

    Shiying Li, Ruirui Zhang, Ying Yuan, Sheng Yi, Qianqian Chen in Molecular Neurobiology (2017)

  14. Article

    Open Access

    Molecular Regulatory Mechanism and Toxicology of Neurodegenerative Processes in MPTP/Probenecid-Induced Progressive Parkinson’s Disease Mice Model Revealed by Transcriptome

    Parkinson’s disease (PD) is a neurodegenerative disease caused by a variety of unclear complex pathogenic factors. The 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine/probenecid (MPTP/p)-induced progressive PD...

    Weiwei Yang, Wenwen Hao, Zhuo Meng, Shiyan Ding, **aodi Li in Molecular Neurobiology (2021)

  15. Article

    Open Access

    The Transcription Factor Ets1 Influences Axonal Growth via Regulation of Lcn2

    Transcription factors are essential for the development and regeneration of the nervous system. The current study investigated key regulatory transcription factors in rat spinal cord development via RNA sequen...

    Miao Gu, **aodi Li, Ronghua Wu, **ao Cheng, Songlin Zhou in Molecular Neurobiology (2024)