13 Result(s)

Article

Deficiency of the HGF/Met pathway leads to thyroid dysgenesis by impeding late thyroid expansion

The mechanisms of bifurcation, a key step in thyroid development, are largely unknown. Here we find three zebrafish lines from a forward genetic screening with similar thyroid dysgenesis phenotypes and identif...

Ya Fang, Jia-** Wan, Zheng Wang, Shi-Yang Song, Cao-Xu Zhang… in Nature Communications (2024)

Article

Autoinducer-2 and bile salts induce c-di-GMP synthesis to repress the T3SS via a T3SS chaperone

Cyclic di-GMP (c-di-GMP) transduces extracellular stimuli into intracellular responses, coordinating a plethora of important biological processes. Low levels of c-di-GMP are often associated with highly virule...

Shuyu Li, Hengxi Sun, Jianghan Li, Yujiao Zhao, Ruiying Wang… in Nature Communications (2022)

Article

Author Correction: A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

Tingting Li, Hongmin Cai, Hebang Yao, Bingjie Zhou, Ning Zhang… in Nature Communications (2022)

Article

A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection

SARS-CoV-2, the causative agent of COVID-19¹, features a receptor-binding domain (RBD) for binding to the host cell ACE2 protein^1–6. Neutralizing antibodies that block RBD-ACE2 interaction are candidates for the ...

Tingting Li, Hongmin Cai, Hebang Yao, Bingjie Zhou, Ning Zhang… in Nature Communications (2021)

Article

Physical activity, screen exposure and sleep among students during the pandemic of COVID-19

This study aimed to determine the levels of health-related behaviours (physical activity, screen exposure and sleep status) among Chinese students from primary, secondary and high schools during the pandemic o...

Yang-feng Guo, Min-qi Liao, Wei-li Cai, **ao-xuan Yu, Shu-na Li… in Scientific Reports (2021)

Article

Tuning lithium-peroxide formation and decomposition routes with single-atom catalysts for lithium–oxygen batteries

Lithium-oxygen batteries with ultrahigh energy density have received considerable attention as of the future energy storage technologies. The development of effective electrocatalysts and a corresponding worki...

Li-Na Song, Wei Zhang, Ying Wang, **n Ge, Lian-Chun Zou… in Nature Communications (2020)

Article

Clinical Application of Artificial Ascites in assisting CT-guided Percutaneous Cryoablation of Hepatic Tumors Adjacent to the Gastrointestinal Tract

This study was to assess the safety and efficacy of artificial ascitetes in assisting CT-guided cryoablation of hepatic tumors adjacent to the gastrointestinal (GI) tract. A total of 84 patients with periphera...

Bing Li, Chuan Liu, **ao-Xue Xu, Yang Li, Yong Du, Chuan Zhang… in Scientific Reports (2017)

Article

Crystal structure of the N-terminal domain of human CDC73 and its implications for the hyperparathyroidism-jaw tumor (HPT-JT) syndrome

CDC73/Parafibromin is a critical component of the Paf1 complex (PAF1C), which is involved in transcriptional elongation and histone modifications. Mutations of the human CDC73/HRPT2 gene are associated with hyper...

Wei Sun, **ao-Lin Kuang, Yan-** Liu, Li-Fei Tian, **ao-Xue Yan… in Scientific Reports (2017)

Article

Identification of key metabolic changes during liver fibrosis progression in rats using a urine and serum metabolomics approach

Reversibility of hepatic fibrosis is an intrinsic response to chronic injury, and with on-going damage, fibrosis can progress to its end-stage consequence, cirrhosis. Non-invasive and reliable biomarkers for e...

Hong Chang, Hong-yu Meng, Shu-min Liu, Yu Wang, **ao-xu Yang, Fang Lu… in Scientific Reports (2017)

Article

Application of the Onodera prognostic nutrition index and neutrophil-to-lymphocyte ratio in risk evaluation of postoperative complications in Crohn’s disease

This study aimed to investigate application of Onodera prognostic nutrition index (OPNI) and neutrophil-to-lymphocyte ratio (NLR) in evaluating risk of postoperative complications in Crohn’s disease (CD). Clin...

Wei-Ming Kang, Chang-Zhen Zhu, **ao-Xu Yang, Jian-Chun Yu… in Scientific Reports (2017)

Article

Netrin-1 promotes glioma growth by activating NF-κB via UNC5A

Gliomas, a common type of brain tumor, are characterized by aggressive infiltration, making it difficultly to cure by surgery. Netrin-1, an extracellular guidance cue critical for neuronal axon path-finding, h...

**g-Ying Chen, **ao-**ao He, Chi Ma, **n-Min Wu, **-Lin Wan… in Scientific Reports (2017)

Article

KIF2A regulates the spindle assembly and the metaphase I-anaphase I transition in mouse oocyte

KIF2A, a member of the kinesin-13 family, has been reported to play a role in spindle assembly in mitosis. However, its function in mammalian meiosis remains unknown. In this research, we examined the expressi...

Ming-Huang Chen, Yu Liu, Ya-Long Wang, Rui Liu, Bai-Hui Xu, Fei Zhang… in Scientific Reports (2016)