20 Result(s)

Article

Exploring plant-derived phytochrome chaperone proteins for light-switchable transcriptional regulation in mammals

Synthetic biology applications require finely tuned gene expression, often mediated by synthetic transcription factors (sTFs) compatible with the human genome and transcriptional regulation mechanisms. While v...

Deqiang Kong, Yang Zhou, Yu Wei, **nyi Wang, Qin Huang… in Nature Communications (2024)

Article

White and gray matter integrity evaluated by MRI-DTI can serve as noninvasive and reliable indicators of structural and functional alterations in chronic neurotrauma

We aimed to evaluate whether white and gray matter microstructure changes observed with magnetic resonance imaging (MRI)-based diffusion tensor imaging (DTI) can be used to reflect the progression of chronic b...

Lan-Wan Wang, Kuan-Hung Cho, Pi-Yu Chao, Li-Wei Kuo, Chia-Wen Chiang… in Scientific Reports (2024)

Article

Global fungal-host interactome map** identifies host targets of candidalysin

Candidalysin, a cytolytic peptide toxin secreted by the human fungal pathogen Candida albicans, is critical for fungal pathogenesis. Yet, its intracellular targets have not been extensively mapped. Here, we perfo...

Tian-Yi Zhang, Yao-Qi Chen, **g-Cong Tan, **-An Zhou… in Nature Communications (2024)

Article

Isolation and characterization of a pangolin-borne HKU4-related coronavirus that potentially infects human-DPP4-transgenic mice

We recently detected a HKU4-related coronavirus in subgenus Merbecovirus (named pangolin-CoV-HKU4-P251T) from a Malayan pangolin¹. Here we report isolation and characterization of pangolin-CoV-HKU4-P251T, the gen...

Luo-Yuan **a, Zhen-Fei Wang, **ao-Ming Cui, Yuan-Guo Li, Run-Ze Ye… in Nature Communications (2024)

Article

Enhanced formation of methane hydrate from active ice with high gas uptake

Gas hydrates provide alternative solutions for gas storage & transportation and gas separation. However, slow formation rate of clathrate hydrate has hindered their commercial development. Here we report a for...

Peng **ao, Juan-Juan Li, Wan Chen, Wei-**n Pang, **ao-Wan Peng… in Nature Communications (2023)

Article

UNC-43/CaMKII-triggered anterograde signals recruit GABA_ARs to mediate inhibitory synaptic transmission and plasticity at C. elegans NMJs

Disturbed inhibitory synaptic transmission has functional impacts on neurodevelopmental and psychiatric disorders. An essential mechanism for modulating inhibitory synaptic transmission is alteration of the po...

Yue Hao, Haowen Liu, **an-Ting Zeng, Ya Wang, Wan-**n Zeng… in Nature Communications (2023)

Article

The interrelationships between neuronal viability, synaptic integrity, microglial responses, and amyloid-beta formation in an in vitro neurotrauma model

The interrelationships between neuronal viability, synaptic integrity, and microglial responses remain in infancy. In dealing with the question, we induced a stretch injury to evaluate the mechanical effects o...

Lan-Wan Wang, Hung-Jung Lin, Chien-Ming Chao, Mao-Tsun Lin… in Scientific Reports (2022)

Article

A self-assembled trimeric protein vaccine induces protective immunity against Omicron variant

The recently emerged Omicron (B.1.1.529) variant has rapidly surpassed Delta to become the predominant circulating SARS-CoV-2 variant, given the higher transmissibility rate and immune escape ability, resultin...

Cai He, **gyun Yang, Weiqi Hong, Zimin Chen, Dandan Peng… in Nature Communications (2022)

Article

A bioactivated in vivo assembly nanotechnology fabricated NIR probe for small pancreatic tumor intraoperative imaging

Real-time imaging of the tumour boundary is important during surgery to ensure that sufficient tumour tissue has been removed. However, the current fluorescence probes for bioimaging suffer from poor tumour sp...

Han Ren, **ang-Zhong Zeng, **ao-**ao Zhao, Da-yong Hou… in Nature Communications (2022)

Article

Author Correction: Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion

Yong-xi Song, **g-xu Sun, Jun-hua Zhao, Yu-chong Yang… in Nature Communications (2021)

Article

The origin and adaptive evolution of domesticated populations of yeast from Far East Asia

The yeast Saccharomyces cerevisiae has been an essential component of human civilization because of its long global history of use in food and beverage fermentation. However, the diversity and evolutionary histor...

Shou-Fu Duan, Pei-Jie Han, Qi-Ming Wang, Wan-Qiu Liu, Jun-Yan Shi… in Nature Communications (2018)

Article

Malignancy risk stratification of thyroid nodules: comparisons of four ultrasound Thyroid Imaging Reporting and Data Systems in surgically resected nodules

To compare the efficiency of four different ultrasound (US) Thyroid Imaging Reporting and Data Systems (TI-RADS) in malignancy risk stratification in surgically resected thyroid nodules (TNs). The study includ...

Ying Wang, Kai-Rong Lei, Ya-** He, **ao-Long Li, Wei-Wei Ren… in Scientific Reports (2017)

Article

Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion

Thousands of genes have been well demonstrated to play important roles in cancer progression. As genes do not function in isolation, they can be grouped into “networks” based on their interactions. In this stu...

Yong-xi Song, **g-xu Sun, Jun-hua Zhao, Yu-chong Yang… in Nature Communications (2017)

Article

Reference genes for quantitative real-time PCR analysis in symbiont Entomomyces delphacidicola of Nilaparvata lugens (Stål)

Nilaparvata lugens (Stål) (Hemiptera: Delphacidae) is a major rice pest that harbors an endosymbiont ascomycete fungus, Entomomyces delphacidicola str. NLU (also known as yeast-like symbiont, YLS). Driving by dem...

Pin-Jun Wan, Yao-Hua Tang, San-Yue Yuan, Jia-Chun He, Wei-**a Wang… in Scientific Reports (2017)

Article

Virtual touch tissue imaging and quantification (VTIQ) in the evaluation of thyroid nodules: the associated factors leading to misdiagnosis

To evaluate the associated factors leading to misdiagnosis with VTIQ for differentiation between benign from malignant thyroid nodules (TNs). The study included 238 benign TNs and 150 malignant TNs. Convention...

Cheng-Yu Sun, Kai-Rong Lei, Bo-Ji Liu, **ao-Wan Bo, **ao-Long Li… in Scientific Reports (2017)

Article

Josephson effects in the junction formed by DIII-class topological and s-wave superconductors with an embedded quantum dot

We investigate the Josephson effects in the junction formed by the indirect coupling between DIII-class topological and s-wave superconductors via an embedded quantum dot. Due to the presence of two kinds of supe...

Zhen Gao, **ao-Qi Wang, Wan-Fei Shan, Hai-Na Wu, Wei-Jiang Gong in Scientific Reports (2016)

Article

Dietary α-linolenic acid-rich flaxseed oil prevents against alcoholic hepatic steatosis via ameliorating lipid homeostasis at adipose tissue-liver axis in mice

Low levels of n-3 polyunsaturated fatty acids (PUFAs) in serum and liver tissue biopsies are the common characteristics in patients with alcoholic liver disease. The α-linolenic acid (ALA) is a plant-derived n...

Meng Wang, **ao-**g Zhang, Kun Feng, Chengwei He, Peng Li… in Scientific Reports (2016)

Article

Comparison between Ultrasound Guided Transperineal and Transrectal Prostate Biopsy: A Prospective, Randomized and Controlled Trial

This prospective study of comparing transperineal prostate biopsy (TPBx) with transrectal prostate biopsy (TRBx) was aimed to provide evidence for clinicians to select the appropriate biopsy approach under dif...

Le-Hang Guo, Rong Wu, Hui-**ong Xu, Jun-Mei Xu, Jian Wu, Shuai Wang… in Scientific Reports (2015)

Article

Scanning focused refractive-index microscopy

We present a novel scanning focused refractive-index microscopy (SFRIM) technique to obtain the refractive index (RI) profiles of objects. The method uses a focused laser as the light source and combines the d...

Teng-Qian Sun, Qing Ye, **ao-Wan Wang, ** Wang, Zhi-Chao Deng… in Scientific Reports (2014)