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  1. Article

    Open Access

    miR-425 deficiency promotes necroptosis and dopaminergic neurodegeneration in Parkinson’s disease

    A major hallmark of Parkinson’s disease (PD) is the degeneration of dopaminergic neurons in the substantia nigra, and the causative mechanism is thought to be the activation of programmed neuronal death. Necro...

    Yong-Bo Hu, Yong-Fang Zhang, Hao Wang, Ru-**g Ren, Hai-Lun Cui… in Cell Death & Disease (2019)

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  2. Article

    Open Access

    ADGRA1 negatively regulates energy expenditure and thermogenesis through both sympathetic nervous system and hypothalamus–pituitary–thyroid axis in male mice

    Adhesion G protein-coupled receptor A1 (ADGRA1, also known as GPR123) belongs to the G protein-coupled receptors (GPCRs) family and is well conserved in the vertebrate lineage. However, the structure of ADGRA1...

    **ao-Hong Zhang, Ling-Yun Tang, **-Yi Wang, Chun-Ling Shen… in Cell Death & Disease (2021)

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  3. Article

    Open Access

    Acinar ATP8b1/LPC pathway promotes macrophage efferocytosis and clearance of inflammation during chronic pancreatitis development

    Noninflammatory clearance of dying cells by professional phagocytes, termed efferocytosis, is fundamental in both homeostasis and inflammatory fibrosis disease but has not been confirmed to occur in chronic pa...

    Wan-jun Yang, Rong-chang Cao, Wang **ao, **ao-lou Zhang, Hao Xu… in Cell Death & Disease (2022)

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