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    Article

    Somatosensory cortex and central amygdala regulate neuropathic pain-mediated peripheral immune response via vagal projections to the spleen

    Pain involves neuroimmune crosstalk, but the mechanisms of this remain unclear. Here we showed that the splenic T helper 2 (TH2) immune cell response is differentially regulated in male mice with acute versus chr...

    **a Zhu, Ji-Ye Huang, Wan-Ying Dong, Hao-Di Tang, Si Xu, Qielan Wu… in Nature Neuroscience (2024)

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    Article

    Distinct thalamocortical circuits underlie allodynia induced by tissue injury and by depression-like states

    In humans, tissue injury and depression can both cause pain hypersensitivity, but whether this involves distinct circuits remains unknown. Here, we identify two discrete glutamatergic neuronal circuits in male...

    **a Zhu, Hao-Di Tang, Wan-Ying Dong, Fang Kang, An Liu, Yu Mao… in Nature Neuroscience (2021)