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  1. Article

    Open Access

    LZTFL1 inhibits kidney tumor cell growth by destabilizing AKT through ZNRF1-mediated ubiquitin proteosome pathway

    LZTFL1 is a tumor suppressor located in chromosomal region 3p21.3 that is deleted frequently and early in various cancer types including the kidney cancer. However, its role in kidney tumorigenesis remains unk...

    Jun Lu, Liang-min Fu, Yun Cao, Yong Fang, Jia-zheng Cao, Yi-hui Pan in Oncogene (2023)

  2. Article

    Open Access

    CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1

    Circular RNAs (circRNAs) play critical roles in clear cell renal cell carcinoma (ccRCC). However, their involvement in sunitinib resistance remains largely unknown. Herein, we identified a novel circRNA, named...

    Ming-xiao Zhang, Jia-li Wang, Cheng-qiang Mo, **ao-peng Mao, Zi-hao Feng in Oncogene (2022)

  3. Article

    Open Access

    A survey of current practices, attitudes and demands of anaesthesiologists regarding the depth of anaesthesia monitoring in China

    In this study, we aimed to analyse survey data to explore two different hypotheses; and for this purpose, we distributed an online survey to Chinese anaesthesiologists. The hypothetical questions in this surve...

    Jian Zhan, Ting-Ting Yi, Zhuo-** Wu, Zong-Hong Long, **ao-Hang Bao in BMC Anesthesiology (2021)

  4. Article

    Open Access

    Pre-transplant donor HBV DNA+ and male recipient are independent risk factors for treatment failure in HBsAg+ donors to HBsAg- kidney transplant recipients

    In order to reduce the burden on organ shortage around the world, using potential infectious donor might be an option. However, scarce evidences have been published on kidney transplantation (KTx) from hepatit...

    **an-ding Wang, Shi-jian Feng, **-peng Liu, Tu-run Song in BMC Infectious Diseases (2021)

  5. Article

    Open Access

    Contrast-enhanced transrectal ultrasound can reduce collection of unnecessary biopsies when diagnosing prostate cancer and is predictive of biochemical recurrence following a radical prostatectomy in patients with localized prostate cancer

    To investigate the value of using contrast-enhanced transrectal ultrasound (CETRUS) to reduce unnecessary collection of biopsies during prostate cancer diagnosis and its utility in predicting biochemical recur...

    Hong-wei Zhao, Jian Li, Jia-Zheng Cao, Juan Lin, Zhu Wang, Jian-yao Lv in BMC Urology (2020)

  6. Article

    Open Access

    Evolutionary de Winter pattern: from de Winter ECG to STEMI-A case report

    De Winter pattern is associated with acute occlusion in the left anterior descending coronary artery combined with upslo** ST-segment depression at the J point in leads V1 through V6 without ST-segment elevatio...

    Hao Wang, **ao-Ce Dai, Yun-Tao Zhao, **ao-Hang Cheng in BMC Cardiovascular Disorders (2020)

  7. Article

    Platycodin D induces apoptosis and triggers ERK- and JNK-mediated autophagy in human hepatocellular carcinoma BEL-7402 cells

    Platycodin D, the main saponin isolated from Chinese herb Platycodonis Radix, exhibits anticancer activities against various cancer cell lines. Here we evaluated its anticancer action against human hepatocellu...

    Ting Li, **ao-huang Xu, Zheng-hai Tang, Ya-fang Wang in Acta Pharmacologica Sinica (2015)

  8. No Access

    Article

    Differentiation of benign and malignant focal liver lesions: value of virtual touch tissue quantification of acoustic radiation force impulse elastography

    The purpose of this study was to investigate the value of virtual tissue quantification (VTQ) of acoustic radiation force impulse elastography for the differential diagnosis of benign and malignant focal liver...

    Le-Hang Guo, Shu-Jun Wang, Hui-**ong Xu, Li-** Sun, Yi-Feng Zhang in Medical Oncology (2015)

  9. No Access

    Article

    Predictive value of vascular endothelial growth factor overexpression in early relapse of colorectal cancer patients after curative resection

    Preclinical and clinical studies have indicated that vascular endothelial growth factor (VEGF) is the predominant angiogenic factor. Recently, there was a consistent trend of poorer survival rates in colorecta...

    Hsiang-Lin Tsai, I-** Yang, Chih-Hung Lin in International Journal of Colorectal Disease (2013)