15 Result(s)

Article

Correction: Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats

**-Hang Gao, Shi-Lei Wen, Shi Feng, Wen-Juan Yang, Yao-Yao Lu, Huan Tong… in Angiogenesis (2023)

Article

Modeling transmission of SARS-CoV-2 Omicron in China

Having adopted a dynamic zero-COVID strategy to respond to SARS-CoV-2 variants with higher transmissibility since August 2021, China is now considering whether, and for how long, this policy can remain in plac...

Jun Cai, **aowei Deng, Juan Yang, Kaiyuan Sun, Hengcong Liu… in Nature Medicine (2022)

Article

Global landscape of SARS-CoV-2 genomic surveillance and data sharing

Genomic surveillance has shaped our understanding of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants. We performed a global landscape analysis on SARS-CoV-2 genomic surveillance and genom...

Zhiyuan Chen, Andrew S. Azman, **nhua Chen, Junyi Zou, Yuyang Tian… in Nature Genetics (2022)

Article

Active DNA end processing in micronuclei of ovarian cancer cells

Ovarian cancer is one of the most deadly gynecological malignancies and inclined to recurrence and drug resistance. Previous studies showed that the tumorigenesis of ovarian cancers and their major histotypes ...

Zizhi Tang, Juan Yang, **n Wang, Ming Zeng, **g Wang, Ao Wang, Mingcai Zhao… in BMC Cancer (2018)

Article

Population pharmacokinetics of moxifloxacin and its concentration–QT interval relationship modeling in Chinese healthy volunteers

Moxifloxacin (MX) is an 8-methoxyquinolone antimicrobial drug, which is often used as a positive control in thorough QT (TQT) studies. In the present study we established the population pharmacokinetics model ...

Feng-yan Xu, Ji-han Huang, Ying-chun He, Li-yu Liang… in Acta Pharmacologica Sinica (2017)

Article

Celecoxib and octreotide synergistically ameliorate portal hypertension via inhibition of angiogenesis in cirrhotic rats

Abnormal angiogenesis is critical for portal hypertension in cirrhosis. Except for etiological treatment, no efficient medication or regime has been explored to treat the early stage of cirrhosis when angiogen...

**-Hang Gao, Shi-Lei Wen, Shi Feng, Wen-Juan Yang, Yao-Yao Lu, Huan Tong… in Angiogenesis (2016)

Article

Timed high-fat diet in the evening affects the hepatic circadian clock and PPARα-mediated lipogenic gene expressions in mice

A long-term high-fat diet may result in a fatty liver. However, whether or not high-fat diets affect the hepatic circadian clock is controversial. The objective of this study is to investigate the effects of t...

**aoyan Wang, Jie Xue, Juan Yang, Meilin **e in Genes & Nutrition (2013)

Article

A cyclic fluctuation model for 24-h ambulatory blood pressure monitoring in Chinese patients with mild to moderate hypertension

The conventional method for analyzing 24-h ambulatory blood pressure monitoring (24-h ABPM) is insufficient to deal with the large amount of data collected. The aim of this study was to develop a novel cyclic ...

Yu-cheng Sheng, Kun Wang, Ling Xu, Juan Yang, Ying-chun He… in Acta Pharmacologica Sinica (2013)

Article

Preoperative Cyfra21-1 and SCC-Ag serum titers predict survival in patients with stage II esophageal squamous cell carcinoma

The purpose of this study is to evaluate the predictive significance of preoperative serum level of cytokeratin 19 fragments (Cyfra21-1) and squamous cell carcinoma antigen (SCC-Ag) after complete resection in...

Xun Cao, Lin Zhang, Gui-Rong Feng, Juan Yang… in Journal of Translational Medicine (2012)

Article

Elevated levels of serum amyloid A indicate poor prognosis in patients with esophageal squamous cell carcinoma

Increase of Serum amyloid A (SAA) level has been observed in patients with a variety of cancers. The objective of this study was to determined whether SAA level could be used as a prognostic parameter in patie...

Jun-Ye Wang, Yu-Zhen Zheng, Juan Yang, Yue-Hao Lin, Shu-Qin Dai, Ge Zhang… in BMC Cancer (2012)

Article

Tyrosine sulfation in N-terminal domain of human C5a receptor is necessary for binding of chemotaxis inhibitory protein of Staphylococcus aureus

Staphylococcus aureus evades host defense through releasing several virulence proteins, such as chemotaxis inhibitory protein of staphylococcus aureus (CHIPS). It has been shown that extracellular N terminus of C...

Zhen-jia Liu, Yan-juan Yang, Lei Jiang, Ying-chun Xu… in Acta Pharmacologica Sinica (2011)

Article

Race differences: modeling the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients

To evaluate race differences in the pharmacodynamics of rosuvastatin in Western and Asian hypercholesterolemia patients using a population pharmacodynamic (PPD) model generated and validated using published cl...

Juan Yang, Lu-** Li, Kun Wang, Ying-chun He, Yu-cheng Sheng… in Acta Pharmacologica Sinica (2011)

Article

A microsatellite polymorphism in IGF1 gene promoter and longevity in a Han Chinese population

Previous studies have suggested a probable association between the polymorphism of a microsatellite locus located in the promoter of IGF1 (Insulin-like growth factor 1) gene and the serum level of IGF1, as wel...

Liang **e, Yuan-ying Gong, Shi-gang Lian, Juan Yang, Shou-jun Gao… in BMC Research Notes (2010)

Article

Phorbol-induced surface expression of NR2A subunit homologues in HEK293 cells

N-methyl-D-aspartate receptors (NMDAR) are heteromeric complexes primarily assembled from NR1 and NR2 subunits. In normal conditions, NR2 sub-units assemble into homodimers in the endoplasmic reticulum (ER). Thes...

Chan-ying Zheng, **u-juan Yang, Zhan-yan Fu, Jian-hong Luo in Acta Pharmacologica Sinica (2006)

Article

Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data

Epigenetic gene silencing is one of the major causes of carcinogenesis. Its widespread occurrence in cancer genome could inactivate many cellular pathways including DNA repair, cell cycle control, apoptosis, c...

Hui-Juan Yang, Vincent WS Liu, Yue Wang, Percy CK Tsang, Hextan YS Ngan in BMC Cancer (2006)