41 Result(s)
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**angjun Sun
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Open AccessEffect of soil bioremediation on soil microbial community structure aimed at controlling tobacco bacterial wilt
Rebuilding soil healthy microbiota is very important for preventing bacterial wilt. A 3-year-long field trial was conducted in China as follows: T1 (conventional fertilization), T2 (T1 + liming), T3 (T1 + bioo...
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Free vibration analysis of beams with an open crack at clamped end by the sub-domain Chebyshev–Ritz method
Free vibration of beams with an open crack at a clamped end, based on the exact, small-strain and linear two-dimensional (2-D) elasticity theory, is studied. The crack is described by a very narrow gap which i...
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Open AccessEffects of salvianolic acid A on intestinal microbiota and lipid metabolism disorders in Zucker diabetic fatty rats
Salvianolic acid A (SalA) is the main water-soluble component isolated from Salvia miltiorrhiza. This study explored the influences of SalA on intestinal microbiota composition and lipid metabolism in Zucker diab...
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5-Aminosalicylic acid ameliorates dextran sulfate sodium-induced colitis in mice by modulating gut microbiota and bile acid metabolism
Colitis develops via the convergence of environmental, microbial, immunological, and genetic factors. The medicine 5-aminosalicylic acid (5-ASA) is widely used in clinical practice for colitis (especially ulce...
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Open AccessIs Physical Activity Associated with Mental Health among Chinese Adolescents during Isolation in COVID-19 Pandemic?
Restricted outdoor activities and online learning during COVID-19 pandemic may pose threats on the physical and mental health of Chinese adolescents in middle schools. The study was to explore the relationship...
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Open AccessAutophagy activated via GRP78 to alleviate endoplasmic reticulum stress for cell survival in blue light-mediated damage of A2E-laden RPEs
Retinal pigment epithelium cells (RPEs) are critical for maintaining retinal homeostasis. Accumulation of age-related lipofuscin, N-retinylidene-N-retinylethanolamine (A2E), makes RPEs vulnerable to blue light...
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Complete genome sequence of an alternavirus from the phytopathogenic fungus Fusarium incarnatum
A novel double-stranded RNA (dsRNA) mycovirus, named “Fusarium incarnatum alternavirus 1” (FiAV1), was found in Fusarium incarnatum strain LY003-07, the causal agent of peony root rot. The complete genome of FiAV...
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Open AccessPhotosensitization of A2E triggers telomere dysfunction and accelerates retinal pigment epithelium senescence
Age-related macular degeneration (AMD) is the leading cause of irreversible vision loss in elderly people. AMD is classified as early, intermediate, advanced non-neovascular, and advanced neovascular forms dep...
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Open AccessCo-contraction characteristics of lumbar muscles in patients with lumbar disc herniation during different types of movement
Muscular performance is an important factor for the mechanical stability of lumbar spine in humans, in which, the co-contraction of lumbar muscles plays a key role. We hypothesized that when executing differen...
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Open AccessFirst comprehensive proteome analysis of lysine crotonylation in seedling leaves of Nicotiana tabacum
Histone crotonylation is a new lysine acylation type of post-translational modification (PTM) enriched at active gene promoters and potential enhancers in yeast and mammalian cells. However, lysine crotonylati...
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Open AccessTP53 mutation-mediated genomic instability induces the evolution of chemoresistance and recurrence in epithelial ovarian cancer
Genomic instability caused by mutation of the checkpoint molecule TP53 may endow cancer cells with the ability to undergo genomic evolution to survive stress and treatment. We attempted to gain insight into the p...
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Open AccessEMMPRIN Down-regulating miR-106a/b Modifies Breast Cancer Stem-like Cell Properties via Interaction with Fibroblasts Through STAT3 and HIF-1α
Extracellular matrix metalloproteinase inducer (EMMPRIN) is a heavily glycosylated protein and expresses in cancer cells widely, which plays important roles in tumor progression. However, the role of EMMPRIN i...
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Open AccessRisk prediction model for epithelial ovarian cancer using molecular markers and clinical characteristics
A high-quality risk prediction model is urgently needed for the clinical management of ovarian cancer. However most existing models are solely based on clinical parameters, and molecular classifications in rec...
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CO2-facilitated transport performance of poly(ionic liquids) in supported liquid membranes
Six types of PILs were designed and synthesized by radical polymerization reaction and ion exchange reaction and the 1H NMR analysis and TG-MS analysis proved the successful procedure and their CO2 permeation pro...
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Progesterone receptor PROGINS and +331G/A polymorphisms confer susceptibility to ovarian cancer: a meta-analysis based on 17 studies
Progesterone and its receptor, progesterone receptor (PGR), have been widely studied for their roles in the onset and development of ovarian cancer. Although numerous epidemiological studies have focused on th...
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Open AccessA high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients
Tumor-associated macrophages (TAMs) are classified into two major phenotypes, M1 and M2. M1 TAMs suppress cancer progression, while M2 TAMs promote it. However, little is known regarding the role of TAMs in th...
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Pharmacokinetics and metabolism of SL-01, a prodrug of gemcitabine, in rats
SL-01, dodecyl-3-((1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl) carbamoyl) pyrazine-2-carboxylate, is a prodrug of gemcitabine. Our previous rep...
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Rheological properties of conductive asphalt binders containing graphite and carbon fiber before and after ageing
Modified asphalt binders were prepared by adding conductive materials, graphite and carbon fiber. The rotation thin film oven test (RTFOT) and pressure age vessel test (PAV) were conducted to simulate the bind...
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Open AccessVegetation evolution and its response to climatic change during 3.15–0.67 Ma in deep-sea pollen record from northern South China Sea
In order to study vegetation evolution and environmental change during 3.15–0.67 Ma, a total of 608 pollen samples with an average time resolution of 4 ka has been analyzed from ODP Site 1145 (water depth 3175...
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Preparation and characterization of a molecularly imprinted polymer by grafting on silica supports: a selective sorbent for patulin toxin
A new molecularly imprinted polymer (MIP) has been prepared on silica beads using the radical “grafting from” polymerization method for selective extraction of minor contaminant mycotoxin of patulin (PTL). Aft...
